The 49ers will play the Rams on Sunday, September 22nd, 2024. The matchup takes place at SoFi Stadium. Watch this exciting Week 3 matchup at 4:25 pm EDT. Check local listings for coverage on FOX.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
The 2024-25 NFL regular season keeps rolling for the San Francisco 49ers and Los Angeles Rams, as they gear up to play an exciting Week 3 matchup at SoFi Stadium. Have a look at the following statistical insights to help you handicap the game.
- SportsBetting3.com Power Rankings - The San Francisco 49ers have started the 2024-25 season with an initial 95.67 power ranking. The Los Angeles Rams currently have a 89.67 power ranking so far.
- Away San Francisco 49ers - Though it's still early in the season, the San Francisco 49ers have a 0-1-0 record as an away team, ranking them 3rd in the league for away team wins.
- Home Los Angeles Rams - Looking at the Los Angeles Rams heading into Week 3, they currently have a 0-0-0 record as a home team. They rank 3rd in the league for home team wins.
- Points Scored - The San Francisco 49ers currently rank 8th (49) up to Week 3, with the Los Angeles Rams ranked 19th (30) for points scored in the 2024-25 regular season.
- Points Against - The San Francisco 49ers stand 11th (42) in the early weeks of the regular season for points against. The Los Angeles Rams rank 2nd (67) for points against.
- Team Records - As Week 3 approaches, the San Francisco 49ers have a 1-1-0 record, with the Los Angeles Rams at 0-2-0 for the 2024-25 NFL regular season.
Captain Shady Lines
A broken compass is right at least twice a day.
Avast, ye scallywags! The San Francisco 49ers be comin' to plunder the Los Angeles Rams!
This Week 3 showdown be takin' place at the grand SoFi Stadium, a battleground fit for warriors.
According to SportsBetting3.com NFL Power Rankings, the 49ers be standin' at 95.67 compared to the Rams' 89.67.
The 49ers be holdin' a 1-1-0 record, while the Rams be strugglin' at 0-2-0. Bet this game at BetRivers, or BetMGM, and review this game's prop bets. Compare the odds below and prepare for a fierce clash on the gridiron!
Best 49ers at Rams Odds
| Underdog Los Angeles Rams | Favorite San Francisco 49ers |
|---|---|
| Over | Under |
|---|---|
| Underdog Los Angeles Rams | Favorite San Francisco 49ers |
|---|---|
Matchup Odds FAQs
The San Francisco 49ers are -6.5 -110 point spread favorites at BetMGM, while the Los Angeles Rams are +6.5 -110 point spread underdogs at BetMGM.
The best over line is 44.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 44.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The San Francisco 49ers are the -300 moneyline favorite at BetMGM and the Los Angeles Rams are the +240 moneyline underdog at BetMGM.
NFL Odds Example
|
Game |
 BetMGMBet |
|---|---|
49ers
Rams
9/22/24 4:25pm EDT | -6.5 -110+6.5 -110 |
Underdog Los Angeles Rams - Los Angeles Rams bettors risk $100 to win $90.91 at -110 odds.
A +6.5 Los Angeles Rams underdog bet wins if they lose by 6 or fewer, tie, or win outright. Your bet loses if they lose by 7 or more.
Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $90.91 at -110 odds.
A -6.5 San Francisco 49ers favorite bet wins if they win by 7 or more. Your bet loses if they win by 6 or fewer, tie, or lose outright.
San Francisco 49ers at Los Angeles Rams Prop Bets
| BetMGM Bet |
|
|---|---|
49ers
Rams
First Team To Score
9/22/24 4:25pm EDT | -160+125Bet |
49ers
Rams
No Touchdown
To Score 1st Touchdown
9/22/24 4:25pm EDT | -200+145+10000Bet |
49ers
Rams
Game to Overtime
9/22/24 4:25pm EDT | Yes +775No -2500Bet |
49ers
Rams
Safety to be Scored
9/22/24 4:25pm EDT | Yes +1000No -3000Bet |
| BetMGM | |
Brock Purdy
Interceptions Thrown
SF at LAR 9/22/24 4:25pm EDT | 0.5 o +1000.5 u -130Bet |
Matthew Stafford
Interceptions Thrown
SF at LAR 9/22/24 4:25pm EDT | 0.5 o -1400.5 u +105Bet |
Brock Purdy
Longest Passing Completion
SF at LAR 9/22/24 4:25pm EDT | 35.5 o -11535.5 u -115Bet |
Matthew Stafford
Longest Passing Completion
SF at LAR 9/22/24 4:25pm EDT | 32.5 o -12032.5 u -110Bet |
| BetMGM | |
Jake Moody
Total Kicking Points
SF at LAR 9/22/24 4:25pm EDT | 7.5 o +1007.5 u -135Bet |
Brock Purdy
Total Pass Completions
SF at LAR 9/22/24 4:25pm EDT | 19.5 o -10519.5 u -125Bet |
Matthew Stafford
Total Pass Completions
SF at LAR 9/22/24 4:25pm EDT | 21.5 o -11521.5 u -115Bet |
Brock Purdy
Total Passing Yards
SF at LAR 9/22/24 4:25pm EDT | 230.5 o -115230.5 u -115Bet |
| BetMGM | |
Matthew Stafford
Total Passing Yards
SF at LAR 9/22/24 4:25pm EDT | 216.5 o -115216.5 u -115Bet |
Brock Purdy
Total Touchdown Passes
SF at LAR 9/22/24 4:25pm EDT | 1.5 o +1001.5 u -135Bet |
Matthew Stafford
Total Touchdown Passes
SF at LAR 9/22/24 4:25pm EDT | 1.5 o +1651.5 u -225Bet |
Recent Meetings Since 2020
| Week | Game | Result | Margin |
|---|---|---|---|
| 2024 Week 15 | Rams vs 49ers Thursday, December 12th, 2024 | LAR 12, SF 6 Levi's Stadium | Rams by 6 |
| 2024 Week 3 | 49ers vs Rams Sunday, September 22nd, 2024 | LAR 27, SF 24 SoFi Stadium | Rams by 3 |
| 2023 Week 18 | Rams vs 49ers Sunday, January 7th, 2024 | LAR 21, SF 20 Levi's Stadium | Rams by 1 |
| 2023 Week 2 | 49ers vs Rams Sunday, September 17th, 2023 | SF 30, LAR 23 SoFi Stadium | 49ers by 7 |
| 2022 Week 8 | 49ers vs Rams Sunday, October 30th, 2022 | SF 31, LAR 14 SoFi Stadium | 49ers by 17 |
| 2022 Week 4 | Rams vs 49ers Monday, October 3rd, 2022 | SF 24, LAR 9 Levi's Stadium | 49ers by 15 |
| 2021 Conference Championship | 49ers vs Rams Sunday, January 30th, 2022 NFC Championship | LAR 20, SF 17 SoFi Stadium | Rams by 3 |
| 2021 Week 18 | 49ers vs Rams Sunday, January 9th, 2022 | SF 27, LAR 24 (OT) SoFi Stadium | 49ers by 3 |
| 2021 Week 10 | Rams vs 49ers Monday, November 15th, 2021 | SF 31, LAR 10 Levi's Stadium | 49ers by 21 |
| 2020 Week 12 | 49ers vs Rams Sunday, November 29th, 2020 | SF 23, LAR 20 SoFi Stadium | 49ers by 3 |
| 2020 Week 6 | Rams vs 49ers Sunday, October 18th, 2020 | SF 24, LAR 16 Levi's Stadium | 49ers by 8 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Los Angeles Rams | 9 | 6 | 0 | 0.600 | 329 | 347 | 4-3-0 | 5-3-0 | 3-1-0 | 0.750 | 5-5-0 | 0.500 | 4W | 4-1-0 |
| San Francisco 49ers | 6 | 8 | 0 | 0.429 | 314 | 320 | 4-4-0 | 2-4-0 | 1-4-0 | 0.200 | 4-6-0 | 0.400 | 1L | 1-4-0 |
San Francisco 49ers & Los Angeles Rams Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
San Francisco 49ers Futures Odds|
Team | BetMGM |
|---|---|
| 49ers | +100000 Bet |
|
Team | BetMGM |
|---|---|
| Rams | +3500 Bet |
San Francisco 49ers & Los Angeles Rams Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Francisco 49ers vs Los Angeles Rams NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 22nd, 2024 at 4:25 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the San Francisco 49ers vs Los Angeles Rams Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the San Francisco 49ers vs Los Angeles Rams Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 22, 2024 NFL Games
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- Philadelphia Eagles vs New Orleans Saints
- Carolina Panthers vs Las Vegas Raiders
- Miami Dolphins vs Seattle Seahawks
- Detroit Lions vs Arizona Cardinals
- Baltimore Ravens vs Dallas Cowboys
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