Detroit Lions vs Arizona Cardinals Odds

The Lions will play the Cardinals on Sunday, September 22nd, 2024. The matchup takes place at State Farm Stadium. Watch this exciting Week 3 matchup at 4:25 pm EDT. Check local listings for coverage on FOX.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

The 2024-25 NFL regular season keeps rolling for the Detroit Lions and Arizona Cardinals, as they gear up to play an exciting Week 3 matchup at State Farm Stadium. Have a look at the following statistical insights to help you handicap the game.

  • SportsBetting3.com Power Rankings - The Detroit Lions have started the 2024-25 season with an initial 94.67 power ranking. The Arizona Cardinals currently have a 97.67 power ranking so far.
  • Away Detroit Lions - Though it's still early in the season, the Detroit Lions have a 0-0-0 record as an away team, ranking them 3rd in the league for away team wins.
  • Home Arizona Cardinals - Looking at the Arizona Cardinals heading into Week 3, they currently have a 1-0-0 record as a home team. They rank 2nd in the league for home team wins.
  • Points Scored - The Detroit Lions currently rank 12th (42) up to Week 3, with the Arizona Cardinals ranked 2nd (69) for points scored in the 2024-25 regular season.
  • Points Against - The Detroit Lions stand 12th (40) in the early weeks of the regular season for points against. The Arizona Cardinals rank 10th (44) for points against.
  • Team Records - As Week 3 approaches, the Detroit Lions have a 1-1-0 record, with the Arizona Cardinals at 1-1-0 for the 2024-25 NFL regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye, me hearties! The Detroit Lions be facing off against the Arizona Cardinals!

State Farm Stadium be the battleground for this crucial Week 3 clash between these two teams.

SportsBetting3.com NFL Power Rankings show the Lions at 94.67 and the Cardinals at 97.67.

The Lions be standing at 1-1-0, while the Cardinals be matching them with a 1-1-0 record.

Bet this game at BetRivers, or BetMGM, review this game's prop bets, and compare the odds below.

Best Lions at Cardinals Odds


Best Point Spread Betting Odds
Underdog

Arizona Cardinals
Favorite

Detroit Lions
The Detroit Lions have a -3 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. The Arizona Cardinals have a +3 -115 point spread at BetMGM OH. The Arizona Cardinals are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 51.5 points. Risk $110 to win $100. BetMGM has the best under line of 51.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Arizona Cardinals
Favorite

Detroit Lions
The Detroit Lions are the -155 moneyline favorite. Risk $155 to win $100 on the Detroit Lions at BetMGM. The Arizona Cardinals are the +130 underdog at BetMGM. Risk $100 to win $130 on the Arizona Cardinals. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Detroit Lions vs Arizona Cardinals NFL game on Sunday, September 22nd, 2024?

The Detroit Lions are -3 -105 point spread favorites at BetMGM, while the Arizona Cardinals are +3 -115 point spread underdogs at BetMGM.

What is the over-under total line for the Detroit Lions vs Arizona Cardinals NFL game on Sunday, September 22nd, 2024?

The best over line is 51.5 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 51.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Detroit Lions vs Arizona Cardinals NFL game on Sunday, September 22nd, 2024?

The Detroit Lions are the -155 moneyline favorite at BetMGM and the Arizona Cardinals are the +130 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Lions
Cardinals
9/22/24 4:25pm EDT
-3 -105+3 -115
Bet $100 at BetMGM Ohio
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Underdog Arizona Cardinals - Arizona Cardinals bettors risk $100 to win $86.96 at -115 odds.

A +3 Arizona Cardinals underdog bet wins if they lose by 2 or fewer, tie, or win outright. The bet pushes if they lose by 3. Your bet loses if they lose by 4 or more.

Favorite Detroit Lions - Detroit Lions bettors risk $100 to win $95.24 at -105 odds.

A -3 Detroit Lions favorite bet wins if they win by 4 or more. The bet pushes if they win by 3. Your bet loses if they win by 2 or fewer, tie, or lose outright.

Detroit Lions at Arizona Cardinals Prop Bets

NFL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Lions
Cardinals
First Team To Score
9/22/24 4:25pm EDT
-125+100Bet
Lions
Cardinals
No Touchdown
To Score 1st Touchdown
9/22/24 4:25pm EDT
-135+100+10000Bet
Lions
Cardinals
Game to Overtime
9/22/24 4:25pm EDT
Yes +700No -2000Bet
Lions
Cardinals
Safety to be Scored
9/22/24 4:25pm EDT
Yes +1000No -3000Bet
BetMGM Sports Betting BetMGM
Jared Goff
Interceptions Thrown
DET at ARI
9/22/24 4:25pm EDT
0.5 o -1150.5 u -115Bet
Kyler Murray
Interceptions Thrown
DET at ARI
9/22/24 4:25pm EDT
0.5 o -1100.5 u -120Bet
Jared Goff
Longest Passing Completion
DET at ARI
9/22/24 4:25pm EDT
35.5 o -12035.5 u -110Bet
Kyler Murray
Longest Passing Completion
DET at ARI
9/22/24 4:25pm EDT
36.5 o -11536.5 u -115Bet
BetMGM Sports Betting BetMGM
Jake Bates
Total Kicking Points
DET at ARI
9/22/24 4:25pm EDT
7.5 o -1207.5 u -110Bet
Matt Prater
Total Kicking Points
DET at ARI
9/22/24 4:25pm EDT
7.5 o +1107.5 u -145Bet
Jared Goff
Total Pass Completions
DET at ARI
9/22/24 4:25pm EDT
23.5 o +10023.5 u -130Bet
Kyler Murray
Total Pass Completions
DET at ARI
9/22/24 4:25pm EDT
21.5 o -12021.5 u -110Bet
BetMGM Sports Betting BetMGM
Jared Goff
Total Passing Yards
DET at ARI
9/22/24 4:25pm EDT
257.5 o -115257.5 u -115Bet
Kyler Murray
Total Passing Yards
DET at ARI
9/22/24 4:25pm EDT
234.5 o -115234.5 u -115Bet
Jared Goff
Total Touchdown Passes
DET at ARI
9/22/24 4:25pm EDT
1.5 o -1451.5 u +110Bet
Kyler Murray
Total Touchdown Passes
DET at ARI
9/22/24 4:25pm EDT
1.5 o +1151.5 u -155Bet

Recent Meetings Since 2020

Recent Meetings Since 2020
WeekGameResultMargin
2024
Week 3
Lions vs Cardinals
Sunday, September 22nd, 2024
DET 20, ARI 13
State Farm Stadium
Lions by 7
2021
Week 15
Cardinals vs Lions
Sunday, December 19th, 2021
DET 30, ARI 12
Ford Field
Lions by 18
2020
Week 3
Lions vs Cardinals
Sunday, September 27th, 2020
DET 26, ARI 23
State Farm Stadium
Lions by 3

Team Standings

2024-2025 NFL Regular Season Standings - Detroit Lions, Arizona Cardinals
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
Detroit Lions6100.8572341343-1-03-0-01-0-01.0005-1-00.8335W5-0-0
Arizona Cardinals4400.5001782052-2-02-2-02-0-01.0002-3-00.4002W3-2-0

Detroit Lions & Arizona Cardinals Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Detroit Lions Futures Odds
2024-25 Detroit Lions Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Lions
+650
Bet
Arizona Cardinals Futures Odds
2024-25 Arizona Cardinals Super Bowl Odds

Team
BetMGM Sports Betting BetMGM
Cardinals
+8000
Bet

Detroit Lions & Arizona Cardinals Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Detroit Lions vs Arizona Cardinals NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 22nd, 2024 at 4:25 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Detroit Lions vs Arizona Cardinals Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Detroit Lions vs Arizona Cardinals Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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