The Guardians will play the Padres on Wednesday, April 2nd, 2025. Your timezone's first pitch time is 4:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The Cleveland Guardians have a 92.67 power ranking. The power ranking for the San Diego Padres is 98.67.
- Visiting Cleveland Guardians - The Cleveland Guardians have a 2-2 record as a visiting team, ranking them 2nd Overall for visiting team wins.
- Home San Diego Padres - The San Diego Padres have a 5-0 record as a home team. They rank 1st for home team wins in the Overall standings.
- Runs Scored - The Cleveland Guardians currently stand 11th (18) Overall, with the San Diego Padres ranking 6th (24) for runs scored.
- Runs Allowed - The Cleveland Guardians are 10th (17) Overall for runs allowed. The San Diego Padres stand 17th (9) for runs allowed.
- Team Streaks - The Cleveland Guardians lost their last game. Meanwhile, the San Diego Padres have won their last 5 games.
- Team Records - The Cleveland Guardians have a 2-2 Overall record (0.0 GB American Central Division), with the San Diego Padres possessing a 5-0 Overall standing (0.5 GB National West Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scurvy dogs! The Cleveland Guardians be facing the San Diego Padres... on Wednesday, April 2nd, 2025. Their sorry record of 2-2 be no match for the Padres' flawless 5-0 streak.
The Guardians better be ready for a fierce battle on enemy territory... against the unstoppable Padres. Their 0.500 win percentage be a joke compared to the Padres' perfection.
If ye be brave enough to bet on this game, head to SportsBetting3.com... and review the odds below. But be warned, the Padres be a force to be reckoned with.
Best Guardians at Padres Odds
| Underdog Cleveland Guardians | Favorite San Diego Padres |
|---|---|
| Over | Under |
|---|---|
| Underdog Cleveland Guardians | Favorite San Diego Padres |
|---|---|
Matchup Odds FAQs
The San Diego Padres are the -185 moneyline favorite at BetMGM and the Cleveland Guardians are the +150 moneyline underdog at BetMGM.
The best over line is 7.5 -115 runs at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 7.5 -105 runs at BetMGM, and that means you risk $105 to win $100 betting the under.
The San Diego Padres are -1.5 +120 run line favorites at BetMGM, while the Cleveland Guardians are +1.5 -145 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Guardians
Padres
4:10pm EDT | +150-185 |
- Cleveland Guardians bettors risk $100 to win $150 at +150 odds. The implied probability for Cleveland Guardians is 40%.
- San Diego Padres bettors risk $100 to win $54.05 at -185 odds. The implied probability for San Diego Padres is 64.91%.
Cleveland Guardians at San Diego Padres Prop Bets
| BetMGM Bet |
|
|---|---|
Guardians
Padres
First Team to Score
4:10pm EDT | -110-118Bet |
Guardians
Padres
Tie
1st Inning Winner
4:10pm EDT | +375+240-135Bet |
Guardians
Padres
Tie
First 3 Innings Winner
4:10pm EDT | +200+100+290Bet |
Guardians
Padres
To Extra Innings
4:10pm EDT | Yes +750No -1200Bet |
| BetMGM | |
Guardians
Padres
1st Team to Score Will Win
4:10pm EDT | Yes -250No +190Bet |
Guardians
Total Runs
CLE at SDG 4:10pm EDT | 3.5 o +1103.5 u -145Bet |
Padres
Total Runs
CLE at SDG 4:10pm EDT | 4.5 o +1104.5 u -145Bet |
Ben Lively
Strikeouts Thrown
CLE at SDG 4:10pm EDT | 3.5 o +1203.5 u -160Bet |
| BetMGM | |
Dylan Cease
Strikeouts Thrown
CLE at SDG 4:10pm EDT | 5.5 o -1605.5 u +125Bet |
Cleveland Guardians & San Diego Padres Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Cleveland Guardians World Series Odds|
Team | BetMGM |
|---|---|
| Guardians | +4000 Bet |
|
Team | BetMGM |
|---|---|
| Padres | +2500 Bet |
Cleveland Guardians & San Diego Padres Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| San Diego Padres | 5 | 0 | 1.000 | +0.5 | 5-0 | 0-0 | 24 | 9 | +15 | W5 | 5-0 |
| Cleveland Guardians | 2 | 2 | 0.500 | +3.0 | 0-0 | 2-2 | 18 | 17 | +1 | L1 | 2-2 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Cleveland Guardians vs San Diego Padres MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Wednesday, April 2nd, 2025 at 4:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Cleveland Guardians vs San Diego Padres Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cleveland Guardians vs San Diego Padres Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other April 2, 2025 MLB Games
- Texas Rangers vs Cincinnati Reds - 12:40pm EDT
- Pittsburgh Pirates vs Tampa Bay Rays - 1:10pm EDT
- Kansas City Royals vs Milwaukee Brewers - 1:10pm EDT
- Los Angeles Angels vs St. Louis Cardinals - 1:15pm EDT
- Washington Nationals vs Toronto Blue Jays - 3:07pm EDT
- Chicago Cubs vs Oakland Athletics - 3:35pm EDT
- San Francisco Giants vs Houston Astros - 4:10pm EDT
- Detroit Tigers vs Seattle Mariners - 4:10pm EDT
- New York Mets vs Miami Marlins - 4:40pm EDT
- Minnesota Twins vs Chicago White Sox - 5:40pm EDT
- Boston Red Sox vs Baltimore Orioles - 6:35pm EDT
- Colorado Rockies vs Philadelphia Phillies - 6:45pm EDT
- Arizona Diamondbacks vs New York Yankees - 7:05pm EDT
- Atlanta Braves vs Los Angeles Dodgers - 8:38pm EDT