San Francisco 49ers vs Carolina Panthers Odds

The 49ers will play the Panthers on Sunday, October 9th, 2022. The matchup takes place at Bank of America Stadium. Watch this exciting Week 5 matchup at 4:05 pm EDT. Check local listings for coverage on CBS.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


Bonus
BetMGM Sportsbook#1 BetMGM
REVIEW
New Customers - Up to $1500 Paid Back in Bonus Bets
Bonus Bets Expire in 7 Days
One new customer offer/Add'l Terms

Bet Now
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Table of Contents

Best 49ers at Panthers Odds


Best Point Spread Betting Odds
Underdog

Carolina Panthers
Favorite

San Francisco 49ers
The San Francisco 49ers have a -6.5 -110 point spread at BetMGM OH. They are the point spread favorite in this matchup. The Carolina Panthers have a +6.5 -110 point spread at BetMGM OH. The Carolina Panthers are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 40 points. Risk $110 to win $100. BetMGM has the best under line of 40 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Carolina Panthers
Favorite

San Francisco 49ers
The San Francisco 49ers are the -275 moneyline favorite. Risk $275 to win $100 on the San Francisco 49ers at BetMGM. The Carolina Panthers are the +220 underdog at BetMGM. Risk $100 to win $220 on the Carolina Panthers. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the San Francisco 49ers vs Carolina Panthers NFL game on Sunday, October 9th, 2022?

The San Francisco 49ers are -6.5 -110 point spread favorites at BetMGM, while the Carolina Panthers are +6.5 -110 point spread underdogs at BetMGM.

What is the over-under total line for the San Francisco 49ers vs Carolina Panthers NFL game on Sunday, October 9th, 2022?

The best over line is 40 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 40 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the San Francisco 49ers vs Carolina Panthers NFL game on Sunday, October 9th, 2022?

The San Francisco 49ers are the -275 moneyline favorite at BetMGM and the Carolina Panthers are the +220 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
49ers
Panthers
10/09/22 4:05pm EDT
-6.5 -110+6.5 -110
Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Underdog Carolina Panthers - Carolina Panthers bettors risk $100 to win $90.91 at -110 odds.

A +6.5 Carolina Panthers underdog bet wins if they lose by 6 or fewer, tie, or win outright. Your bet loses if they lose by 7 or more.

Favorite San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $90.91 at -110 odds.

A -6.5 San Francisco 49ers favorite bet wins if they win by 7 or more. Your bet loses if they win by 6 or fewer, tie, or lose outright.

San Francisco 49ers at Carolina Panthers Prop Bets

NFL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
49ers
Panthers
10/09/22 4:05pm EDT
Pending BetMGM

Recent Meetings Since 2018

Recent Meetings Since 2018
WeekGameResultMargin
2022
Week 5
49ers vs Panthers
Sunday, October 9th, 2022
SF 37, CAR 15
Bank of America Stadium
49ers by 22
2019
Week 8
Panthers vs 49ers
Sunday, October 27th, 2019
SF 51, CAR 13
Levi's Stadium
49ers by 38

Team Standings

2022-2023 NFL Regular Season Standings - San Francisco 49ers, Carolina Panthers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xz - San Francisco 49ers13400.7654502778-1-05-3-06-0-01.00010-2-00.83310W5-0-0
Carolina Panthers71000.4123473745-4-02-6-04-2-00.6676-6-00.5001W3-2-0

San Francisco 49ers & Carolina Panthers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

San Francisco 49ers Futures Odds

No Super Bowl TM San Francisco 49ers YR: futures available

Carolina Panthers Futures Odds

No Super Bowl TM Carolina Panthers YR: futures available

San Francisco 49ers & Carolina Panthers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Francisco 49ers vs Carolina Panthers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Sunday, October 9th, 2022 at 4:05 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the San Francisco 49ers vs Carolina Panthers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the San Francisco 49ers vs Carolina Panthers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other October 9, 2022 NFL Games

Odds Preview 754