Detroit Lions vs San Francisco 49ers Odds

The Lions will play the 49ers on Monday, December 30th, 2024. The matchup takes place at Levi's Stadium. Watch this exciting Week 17 matchup at 7:15 pm CST. Check local listings for coverage on ESPN, ABC, ESPN+.

Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.


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Table of Contents

Key Matchup Stats

The 2024-25 NFL regular season is winding down. One of the upcoming Week 17 matchups includes a battle between the Detroit Lions and San Francisco 49ers . Set for Monday, December 30th, 2024 at Levi's Stadium, the result of this game may affect this season's playoff picture. Take note of each team's performance stats below. Any late-season momentum will likely carryover into the playoffs.

  • SportsBetting3.com Power Rankings - Looking at Week 17 of the 2024-25 NFL regular season, the Detroit Lions have a 98.00 power ranking based on our formula. The San Francisco 49ers currently possess a 90.00 power ranking as the regular season wraps up.
  • Away Detroit Lions - The Detroit Lions have a 7-0-0 record as an away team for the 2024-25 regular season, ranking them 1st in the league for away team wins.
  • Home San Francisco 49ers - As for the San Francisco 49ers, they come to this Week 17 game with a 4-4-0 record as a home team. They rank 5th in the league for home team wins.
  • Points Scored - The Detroit Lions currently rank 1st (493) as we approach Week 17, with the San Francisco 49ers ranked 16th (331) for points scored to date.
  • Points Against - With the regular season concluding, the Detroit Lions rank 22nd (299) for points score against them. Note that the San Francisco 49ers now rank 12th (349) for points scored against.
  • Team Records - The final games of the season will determine who heads to the playoffs. As Week 17 action looms, the Detroit Lions have a 13-2-0 record, with the San Francisco 49ers at 6-9-0 for the 2024-25 NFL regular season.

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye! The Detroit Lions be facing the San Francisco 49ers on December 30th. The NFL regular season be nearin' its end for these two teams. This game be critical for the playoff picture, so prepare for battle!

The Lions be holdin' a 13-2-0 record, while the 49ers be standin' at 6-9-0. Detroit be dominatin' the NFC North Division with a 5-0-0 record. The 49ers be strugglin' in the NFC West Division with a 1-4-0 record.

This Week 17 showdown be happenin' at Levi's Stadium, so be ready for a fierce fight. The SportsBetting3.com NFL Power Rankings show the Lions at 98.00 and the 49ers at 90.00.

BetRivers and BetMGM be the best legal NFL sportsbooks, so place yer bets wisely. We've gathered this matchup's prop bets below, so choose yer picks carefully. Review the best point spread, total, and moneyline odds for this matchup in the following tables. Let the battle begin on the gridiron!

Best Lions at 49ers Odds


Best Point Spread Betting Odds
Underdog

San Francisco 49ers
Favorite

Detroit Lions
The Detroit Lions have a -3.5 -110 point spread at BetRivers PA. They are the point spread favorite in this matchup. The San Francisco 49ers have a +4 -105 point spread at BetMGM PA. The San Francisco 49ers are the point spread underdogs. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 50 points. Risk $110 to win $100. BetRivers has the best under line of 50 points. Risk $108 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

San Francisco 49ers
Favorite

Detroit Lions
The Detroit Lions are the -225 moneyline favorite. Risk $225 to win $100 on the Detroit Lions at BetRivers. The San Francisco 49ers are the +200 underdog at BetMGM. Risk $100 to win $200 on the San Francisco 49ers. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Detroit Lions vs San Francisco 49ers NFL game on Monday, December 30th, 2024?

The Detroit Lions are -3.5 -110 point spread favorites at BetRivers, while the San Francisco 49ers are +4 -105 point spread underdogs at BetMGM.

What is the over-under total line for the Detroit Lions vs San Francisco 49ers NFL game on Monday, December 30th, 2024?

The best over line is 50 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 50 -108 points at BetRivers, and that means you risk $108 to win $100 betting the under.

What is the moneyline for the Detroit Lions vs San Francisco 49ers NFL game on Monday, December 30th, 2024?

The Detroit Lions are the -225 moneyline favorite at BetRivers and the San Francisco 49ers are the +200 moneyline underdog at BetMGM.

NFL Odds Example

NFL Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Lions
49ers
12/30/24 7:15pm CST
-4 -115+4 -105
Bet $100 at BetMGM Pennsylvania
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Underdog San Francisco 49ers - San Francisco 49ers bettors risk $100 to win $95.24 at -105 odds.

A +4 San Francisco 49ers underdog bet wins if they lose by 3 or fewer, tie, or win outright. The bet pushes if they lose by 4. Your bet loses if they lose by 5 or more.

Favorite Detroit Lions - Detroit Lions bettors risk $100 to win $86.96 at -115 odds.

A -4 Detroit Lions favorite bet wins if they win by 5 or more. The bet pushes if they win by 4. Your bet loses if they win by 3 or fewer, tie, or lose outright.

Detroit Lions at San Francisco 49ers Prop Bets

NFL Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Lions
49ers
First Team To Score
12/30/24 7:15pm CST
-140+110Bet
Lions
49ers
No Touchdown
To Score 1st Touchdown
12/30/24 7:15pm CST
-160+120+10000Bet
Lions
49ers
Game to Overtime
12/30/24 7:15pm CST
Yes +750No -2500Bet
Lions
49ers
Safety to be Scored
12/30/24 7:15pm CST
Yes +1000No -3000Bet
BetMGM Sports Betting BetMGM
Brock Purdy
Interceptions Thrown
DET at SF
12/30/24 7:15pm CST
0.5 o -1450.5 u +110Bet
Jared Goff
Interceptions Thrown
DET at SF
12/30/24 7:15pm CST
0.5 o +1200.5 u -160Bet
Brock Purdy
Longest Passing Completion
DET at SF
12/30/24 7:15pm CST
37.5 o -12037.5 u -110Bet
Jared Goff
Longest Passing Completion
DET at SF
12/30/24 7:15pm CST
34.5 o -12034.5 u -110Bet
BetMGM Sports Betting BetMGM
Jake Bates
Total Kicking Points
DET at SF
12/30/24 7:15pm CST
7.5 o -1307.5 u -105Bet
Jake Moody
Total Kicking Points
DET at SF
12/30/24 7:15pm CST
6.5 o -1256.5 u -105Bet
Brock Purdy
Total Pass Completions
DET at SF
12/30/24 7:15pm CST
21.5 o -10521.5 u -125Bet
Jared Goff
Total Pass Completions
DET at SF
12/30/24 7:15pm CST
22.5 o -12522.5 u -105Bet
BetMGM Sports Betting BetMGM
Brock Purdy
Total Passing Yards
DET at SF
12/30/24 7:15pm CST
254.5 o -115254.5 u -115Bet
Jared Goff
Total Passing Yards
DET at SF
12/30/24 7:15pm CST
247.5 o -115247.5 u -115Bet
Brock Purdy
Total Touchdown Passes
DET at SF
12/30/24 7:15pm CST
1.5 o -1301.5 u -105Bet
Jared Goff
Total Touchdown Passes
DET at SF
12/30/24 7:15pm CST
1.5 o -1501.5 u +110Bet

Recent Meetings Since 2020

Recent Meetings Since 2020
WeekGameResultMargin
2024
Week 17
Lions vs 49ers
Monday, December 30th, 2024
DET 40, SF 34
Levi's Stadium
Lions by 6
2023
Conference Championship
Lions vs 49ers
Sunday, January 28th, 2024
NFC Championship
SF 34, DET 31
Levi's Stadium
49ers by 3
2021
Week 1
49ers vs Lions
Sunday, September 12th, 2021
SF 41, DET 33
Ford Field
49ers by 8

Team Standings

2024-2025 NFL Regular Season Standings - Detroit Lions, San Francisco 49ers
Team W L T Pct PF PA Home Away Div Div% Conf Conf% Strk L5
xz* - Detroit Lions15200.8825643427-2-08-0-06-0-01.00011-1-00.9173W4-1-0
San Francisco 49ers61100.3533894364-5-02-6-01-5-00.1674-8-00.3334L1-4-0

Detroit Lions & San Francisco 49ers Futures Odds

Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.

Detroit Lions Futures Odds

No Super Bowl TM Detroit Lions YR: futures available

San Francisco 49ers Futures Odds

No Super Bowl TM San Francisco 49ers YR: futures available

Detroit Lions & San Francisco 49ers Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Detroit Lions vs San Francisco 49ers NFL Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Monday, December 30th, 2024 at 7:15 pm CST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's NFL page, look for the Detroit Lions vs San Francisco 49ers Game.

    Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Detroit Lions vs San Francisco 49ers Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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