The Cardinals will play the Bills on Sunday, September 8th, 2024. The matchup takes place at Highmark Stadium. Watch this exciting Week 1 matchup at 1:00 pm EDT. Check local listings for coverage on CBS.
Learn more about NFL betting with our handy tutorial and guide. Know when to bet the spread, moneyline, totals or props.
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Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Recent Meetings
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
It's early in the 2024-25 NFL regular season for the Arizona Cardinals and Buffalo Bills. Let's review some stats from the 2023 regular season to get an idea of how these teams will fare.
- SportsBetting3.com Power Rankings - The Arizona Cardinals had a 87.33 power ranking in the 2023 regular season. The power ranking for the Buffalo Bills in the 2023 regular season was 98.33.
- Away Arizona Cardinals - At the end of the 2023 regular season, the Arizona Cardinals had a 2-7-0 record as an away team, ranking them 6th in the regular season for away team wins.
- Home Buffalo Bills - The Buffalo Bills finished the 2023 regular season with a 7-2-0 record as a home team. They ranked 2nd for home team wins in the regular season standings.
- Points Scored - The Arizona Cardinals wound up 22nd (330) in the regular season, with the Buffalo Bills ranked 6th (451) for points scored in the 2023 regular season.
- Points Against - The Arizona Cardinals finished 2nd (455) in the regular season for points against. The Buffalo Bills wound up 28th (311) in the 2023 regular season for points against.
- Team Records - The Arizona Cardinals had a 4-13-0 regular season record, with the Buffalo Bills notching a 11-6-0 regular season standing last year.
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye scallywags! The Arizona Cardinals be sailin' to Highmark Stadium to battle the Bills. The Cardinals be lookin' to plunder a win after a dismal season.
But beware, the Bills be a fierce foe, with a strong record last season. The battle between these two teams be sure to be a nail-biter.
If ye be feelin' lucky, head over to SportsBetting3.com to bet on this game. Ye can review the odds below and put yer doubloons on the line. May the best team win on the gridiron!
Best Cardinals at Bills Odds
| Underdog Arizona Cardinals | Favorite Buffalo Bills |
|---|---|
| Over | Under |
|---|---|
| Underdog Arizona Cardinals | Favorite Buffalo Bills |
|---|---|
Matchup Odds FAQs
The Buffalo Bills are -6.5 -115 point spread favorites at BetMGM, while the Arizona Cardinals are +6.5 -105 point spread underdogs at BetMGM.
The best over line is 46 -110 points at BetMGM, which means you risk $110 to win $100 betting the over. The best under line is 46 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.
The Buffalo Bills are the -300 moneyline favorite at BetMGM and the Arizona Cardinals are the +240 moneyline underdog at BetMGM.
NFL Odds Example
|
Game |
 BetMGMBet |
|---|---|
Cardinals
Bills
9/08/24 1:00pm EDT | +6.5 -105-6.5 -115 |
Underdog Arizona Cardinals - Arizona Cardinals bettors risk $100 to win $95.24 at -105 odds.
A +6.5 Arizona Cardinals underdog bet wins if they lose by 6 or fewer, tie, or win outright. Your bet loses if they lose by 7 or more.
Favorite Buffalo Bills - Buffalo Bills bettors risk $100 to win $86.96 at -115 odds.
A -6.5 Buffalo Bills favorite bet wins if they win by 7 or more. Your bet loses if they win by 6 or fewer, tie, or lose outright.
Arizona Cardinals at Buffalo Bills Prop Bets
| BetMGM Bet |
|
|---|---|
Cardinals
Bills
First Team To Score
9/08/24 1:00pm EDT | +135-175Bet |
Cardinals
Bills
No Touchdown
To Score 1st Touchdown
9/08/24 1:00pm EDT | +145-200+10000Bet |
Cardinals
Bills
Game to Overtime
9/08/24 1:00pm EDT | Yes +800No -3000Bet |
Cardinals
Bills
Safety to be Scored
9/08/24 1:00pm EDT | Yes +1000No -3000Bet |
| BetMGM | |
Cardinals
Team Total Points
ARI at BUF 9/08/24 1:00pm EDT | 21.5 o +11021.5 u -145Bet |
Bills
Team Total Points
ARI at BUF 9/08/24 1:00pm EDT | 27.5 o +10027.5 u -125Bet |
Josh Allen
Total Passing Yards
ARI at BUF 9/08/24 1:00pm EDT | 244.5 o -115244.5 u -115Bet |
Josh Allen
Interceptions Thrown
ARI at BUF 9/08/24 1:00pm EDT | 0.5 o -1100.5 u -120Bet |
| BetMGM | |
Josh Allen
Longest Passing Completion
ARI at BUF 9/08/24 1:00pm EDT | 35.5 o -12035.5 u -110Bet |
Josh Allen
Total Touchdown Passes
ARI at BUF 9/08/24 1:00pm EDT | 1.5 o -1251.5 u -105Bet |
Kyler Murray
Interceptions Thrown
ARI at BUF 9/08/24 1:00pm EDT | 0.5 o -1350.5 u +100Bet |
Kyler Murray
Total Passing Yards
ARI at BUF 9/08/24 1:00pm EDT | 225.5 o -115225.5 u -115Bet |
| BetMGM | |
Kyler Murray
Longest Passing Completion
ARI at BUF 9/08/24 1:00pm EDT | 33.5 o -11533.5 u -120Bet |
Kyler Murray
Total Touchdown Passes
ARI at BUF 9/08/24 1:00pm EDT | 1.5 o +1201.5 u -160Bet |
Kyler Murray
Total Pass Completions
ARI at BUF 9/08/24 1:00pm EDT | 21.5 o -12521.5 u -105Bet |
Matt Prater
Total Kicking Points
ARI at BUF 9/08/24 1:00pm EDT | 5.5 o -1255.5 u -105Bet |
| BetMGM | |
Tyler Bass
Total Kicking Points
ARI at BUF 9/08/24 1:00pm EDT | 7.5 o +1057.5 u -140Bet |
Recent Meetings Since 2020
| Week | Game | Result | Margin |
|---|---|---|---|
| 2024 Week 1 | Cardinals vs Bills Sunday, September 8th, 2024 | BUF 34, ARI 28 Highmark Stadium | Bills by 6 |
| 2020 Week 10 | Bills vs Cardinals Sunday, November 15th, 2020 | ARI 32, BUF 30 State Farm Stadium | Cardinals by 2 |
Team Standings
| Team | W | L | T | Pct | PF | PA | Home | Away | Div | Div% | Conf | Conf% | Strk | L5 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Buffalo Bills | 2 | 0 | 0 | 1.000 | 65 | 38 | 1-0-0 | 1-0-0 | 1-0-0 | 1.000 | 1-0-0 | 1.000 | 2W | 2-0-0 |
| Arizona Cardinals | 1 | 1 | 0 | 0.500 | 69 | 44 | 1-0-0 | 0-1-0 | 1-0-0 | 1.000 | 1-0-0 | 1.000 | 1W | 1-1-0 |
Arizona Cardinals & Buffalo Bills Futures Odds
Here are each team's Super Bowl, conference, and division futures odds. Review odds for other matchups and learn the best NFL bets.
Arizona Cardinals Futures Odds|
Team | BetMGM |
|---|---|
| Cardinals | +6600 Bet |
|
Team | BetMGM |
|---|---|
| Bills | +1100 Bet |
Arizona Cardinals & Buffalo Bills Team Pages
Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Arizona Cardinals vs Buffalo Bills NFL Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 8th, 2024 at 1:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's NFL page, look for the Arizona Cardinals vs Buffalo Bills Game.
Navigate to the sportsbook's NFL page. Next, look for live or upcoming matchups. Select the Arizona Cardinals vs Buffalo Bills Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 8, 2024 NFL Games
| Matchup | Date & Time |
|---|---|
| Houston Texans vs Indianapolis Colts | 9/08/24 1:00pm EDT |
| Carolina Panthers vs New Orleans Saints | 9/08/24 1:00pm EDT |
| Jacksonville Jaguars vs Miami Dolphins | 9/08/24 1:00pm EDT |
| New England Patriots vs Cincinnati Bengals | 9/08/24 1:00pm EDT |
| Pittsburgh Steelers vs Atlanta Falcons | 9/08/24 1:00pm EDT |
| Minnesota Vikings vs New York Giants | 9/08/24 1:00pm EDT |
| Tennessee Titans vs Chicago Bears | 9/08/24 1:04pm EDT |
| Las Vegas Raiders vs Los Angeles Chargers | 9/08/24 4:05pm EDT |
| Denver Broncos vs Seattle Seahawks | 9/08/24 4:05pm EDT |
| Dallas Cowboys vs Cleveland Browns | 9/08/24 4:25pm EDT |
| Washington Commanders vs Tampa Bay Buccaneers | 9/08/24 4:25pm EDT |
| Los Angeles Rams vs Detroit Lions | 9/08/24 8:20pm EDT |