The Orange will play the Cardinals on Saturday, November 13th, 2021. The matchup takes place at Cardinal Stadium. Watch this exciting Week 11 matchup at 12:00 pm EST. Check local listings for coverage on ESPN3.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Best Orange at Cardinals Odds

**Best Point Spread Betting Odds**
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Syracuse at Louisville Prop Bets

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College Football Prop Bets
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	BetMGM Bet
Syracuse Louisville 11/13/21 12:00pm EST	Pending BetMGM

Recent Meetings Since 2017

Recent Meetings Since 2017
Week	Game	Result	Margin
2022 Week 1	Louisville vs Syracuse Saturday, September 3rd, 2022	SYR 31, LOU 7 JMA Wireless Dome	Syracuse by 24
2021 Week 11	Syracuse vs Louisville Saturday, November 13th, 2021	LOU 41, SYR 3 Cardinal Stadium	Louisville by 38
2020 Week 12	Syracuse vs Louisville Friday, November 20th, 2020	LOU 30, SYR 0 Cardinal Stadium	Louisville by 30
2019 Week 13	Syracuse vs Louisville Saturday, November 23rd, 2019	LOU 56, SYR 34 Cardinal Stadium	Louisville by 22
2018 Week 11	Louisville vs Syracuse Friday, November 9th, 2018	SYR 54, LOU 23 JMA Wireless Dome	Syracuse by 31
2017 Week 12	Syracuse vs Louisville Saturday, November 18th, 2017	LOU 56, SYR 10 Cardinal Stadium	Louisville by 46

Team Standings

2021-2022 College Football Regular Season Standings - Syracuse, Louisville
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
Louisville	4-4	0.500	6	7	411	355	4-3	2-2	L2
Syracuse	2-6	0.250	5	7	299	316	3-4	2-3	L3

Syracuse & Louisville Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Syracuse Championship Odds

No NCAA College Football Championship TM Syracuse YR: futures available

Louisville Championship Odds

2024-25 Louisville NCAA College Football Championship Odds
Team	BetMGM
Louisville

Syracuse & Louisville Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2021-22 Syracuse Games & Results
Week	Matchup	Date & Result
Week 1	Syracuse vs Ohio	SYR 29, OHIO 9 Saturday, September 4th, 2021
Week 2	Rutgers vs Syracuse	RUTG 17, SYR 7 Saturday, September 11th, 2021
Week 3	Albany vs Syracuse	SYR 62, ALB 24 Saturday, September 18th, 2021
Week 4	Liberty vs Syracuse	SYR 24, LIB 21 Friday, September 24th, 2021
Week 5	Syracuse vs Florida State	FSU 33, SYR 30 Saturday, October 2nd, 2021
Week 6	Wake Forest vs Syracuse	WAKE 40, SYR 37 (OT) Saturday, October 9th, 2021
Week 7	Clemson vs Syracuse	CLEM 17, SYR 14 Friday, October 15th, 2021
Week 8	Syracuse vs Virginia Tech	SYR 41, VT 36 Saturday, October 23rd, 2021
Week 9	Boston College vs Syracuse	SYR 21, BC 6 Saturday, October 30th, 2021
Week 11	Syracuse vs Louisville	LOU 41, SYR 3 Saturday, November 13th, 2021
Week 12	Syracuse vs NC State	NCST 41, SYR 17 Saturday, November 20th, 2021
Week 13	Pittsburgh vs Syracuse	PITT 31, SYR 14 Saturday, November 27th, 2021

2021-22 Louisville Games & Results
Week	Matchup	Date & Result
Week 1	Louisville vs Ole Miss	MISS 43, LOU 24 Monday, September 6th, 2021
Week 2	Eastern Kentucky vs Louisville	LOU 30, EKU 3 Saturday, September 11th, 2021
Week 3	UCF vs Louisville	LOU 42, UCF 35 Friday, September 17th, 2021
Week 4	Louisville vs Florida State	LOU 31, FSU 23 Saturday, September 25th, 2021
Week 5	Louisville vs Wake Forest	WAKE 37, LOU 34 Saturday, October 2nd, 2021
Week 6	Virginia vs Louisville	UVA 34, LOU 33 Saturday, October 9th, 2021
Week 8	Boston College vs Louisville	LOU 28, BC 14 Saturday, October 23rd, 2021
Week 9	Louisville vs NC State	NCST 28, LOU 13 Saturday, October 30th, 2021
Week 10	Clemson vs Louisville	CLEM 30, LOU 24 Saturday, November 6th, 2021
Week 11	Syracuse vs Louisville	LOU 41, SYR 3 Saturday, November 13th, 2021
Week 12	Louisville vs Duke	LOU 62, DUKE 22 Thursday, November 18th, 2021
Week 13	Kentucky vs Louisville	UK 52, LOU 21 Saturday, November 27th, 2021
Bowls	Air Force vs Louisville Servpro First Responder Bowl	AFA 31, LOU 28 Tuesday, December 28th, 2021

How to Bet on the Game

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How to Bet on the Syracuse vs Louisville College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 13th, 2021 at 12:00 pm EST, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Syracuse vs Louisville Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Syracuse vs Louisville Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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