The Golden Eagles will play the Crimson Tide on Saturday, September 25th, 2021. The matchup takes place at Bryant-Denny Stadium. Watch this exciting Week 4 matchup at 7:30 pm EDT. Check local listings for coverage on SECN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

STATE	Bonus
#1 BetMGM REVIEW	New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966

Best Odds
Interactive Odds Example
Prop Bets
Recent Meetings
Team Standings
Futures Odds
Team Pages
Team Schedules & Results
Other Games Today

Best Golden Eagles at Crimson Tide Odds

**Best Point Spread Betting Odds**
TBD	TBD

Point Spread odds are updating, please check back soon.

**Best Total Betting Odds**
Over	Under

Total odds are updating, please check back soon.

**Best Moneyline Betting Odds**
TBD	TBD

Moneyline odds are updating, please check back soon.

College Football Odds Example

College Football Odds and Outcomes Explained
Game	Book

Southern Miss at Alabama Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
	BetMGM Bet
Southern Miss Alabama 9/25/21 7:30pm EDT	Pending BetMGM

Recent Meetings Since 2017

Recent Meetings Since 2017
Week	Game	Result	Margin
2021 Week 4	Southern Miss vs Alabama Saturday, September 25th, 2021	ALA 63, USM 14 Bryant-Denny Stadium	Alabama by 49
2019 Week 4	Southern Miss vs Alabama Saturday, September 21st, 2019	ALA 49, USM 7 Bryant-Denny Stadium	Alabama by 42

Team Standings

2021-2022 College Football Regular Season Standings - Southern Miss, Alabama
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
C-USA West
Southern Miss	2-6	0.250	3	9	212	335	2-4	1-5	W2
SEC West
#2 Alabama	7-1	0.875	13	2	598	302	7-0	3-1	L1

Southern Miss & Alabama Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Southern Miss Championship Odds

No NCAA College Football Championship TM Southern Miss YR: futures available

Alabama Championship Odds

2024-25 Alabama NCAA College Football Championship Odds
Team	BetMGM
Alabama	+750 Bet

Southern Miss & Alabama Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2021-22 Southern Miss Games & Results
Week	Matchup	Date & Result
Week 1	Southern Miss vs South Alabama	USA 31, USM 7 Saturday, September 4th, 2021
Week 2	Grambling State vs Southern Miss	USM 37, GRAM 0 Saturday, September 11th, 2021
Week 3	Troy vs Southern Miss	TROY 21, USM 9 Saturday, September 18th, 2021
Week 4	Southern Miss vs Alabama	ALA 63, USM 14 Saturday, September 25th, 2021
Week 5	Southern Miss vs Rice	RICE 24, USM 19 Saturday, October 2nd, 2021
Week 6	UTEP vs Southern Miss	UTEP 26, USM 13 Saturday, October 9th, 2021
Week 7	UAB vs Southern Miss	UAB 34, USM 0 Saturday, October 16th, 2021
Week 9	Southern Miss vs Middle Tennessee	MTSU 35, USM 10 Saturday, October 30th, 2021
Week 10	North Texas vs Southern Miss	UNT 38, USM 14 Saturday, November 6th, 2021
Week 11	Southern Miss vs UTSA	UTSA 27, USM 17 Saturday, November 13th, 2021
Week 12	Southern Miss vs Louisiana Tech	USM 35, LT 19 Friday, November 19th, 2021
Week 13	FIU vs Southern Miss	USM 37, FIU 17 Saturday, November 27th, 2021

2021-22 Alabama Games & Results
Week	Matchup	Date & Result
Week 1	Alabama vs Miami (FL)	ALA 44, MIA 13 Saturday, September 4th, 2021
Week 2	Mercer vs Alabama	ALA 48, MER 14 Saturday, September 11th, 2021
Week 3	Alabama vs Florida	ALA 31, FLA 29 Saturday, September 18th, 2021
Week 4	Southern Miss vs Alabama	ALA 63, USM 14 Saturday, September 25th, 2021
Week 5	Ole Miss vs Alabama	ALA 42, MISS 21 Saturday, October 2nd, 2021
Week 6	Alabama vs Texas A&M	TA&M 41, ALA 38 Saturday, October 9th, 2021
Week 7	Alabama vs Mississippi State	ALA 49, MSST 9 Saturday, October 16th, 2021
Week 8	Tennessee vs Alabama	ALA 52, TENN 24 Saturday, October 23rd, 2021
Week 10	LSU vs Alabama	ALA 20, LSU 14 Saturday, November 6th, 2021
Week 11	New Mexico State vs Alabama	ALA 59, NMSU 3 Saturday, November 13th, 2021
Week 12	Arkansas vs Alabama	ALA 42, ARK 35 Saturday, November 20th, 2021
Week 13	Alabama vs Auburn	ALA 24, AUB 22 (4OT) Saturday, November 27th, 2021
Week 14	Georgia vs Alabama	ALA 41, UGA 24 Saturday, December 4th, 2021
Bowls	Cincinnati vs Alabama CFP Semifinal At The Goodyear Cotton Bowl Classic	ALA 27, CIN 6 Friday, December 31st, 2021
Bowls	Georgia vs Alabama CFP National Championship Pres. By AT&T	UGA 33, ALA 18 Monday, January 10th, 2022

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Southern Miss vs Alabama College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 25th, 2021 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Southern Miss vs Alabama Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Southern Miss vs Alabama Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other September 25, 2021 NCAAFB Games

Odds Preview 1410

Southern Miss vs Alabama Football Odds

Table of Contents