Louisville vs Clemson Football Odds

The Cardinals will play the Tigers on Saturday, November 2nd, 2024. The matchup takes place at Memorial Stadium (Clemson, SC). Watch this exciting Week 10 matchup at 7:30 pm EDT. Check local listings for coverage on ESPN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Matchup Stats
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Key Matchup Stats

It's now the back half of the 2024 college football season, as we begin looking towards the annual bowl games and college football playoffs. Week 10 action features a matchup between Louisville and Clemson, kicking off at Memorial Stadium (Clemson, SC) on Saturday, November 2nd, 2024. Have a look at the following season performance stats to better handicap this game.

SportsBetting3.com Power Rankings - Louisville has a 94.67 conference power ranking for the 2024 season. The conference power ranking for Clemson is 97.67.
Away Louisville - As Week 10 looms, Louisville currently has a 2-1 record as an away team for the 2024 regular season. This ranks them 3rd in the ACC Conference for away team wins. Remember that a team's overall record and schedule strength will affect whether or not they make a bowl game or the playoffs.
Home Clemson - Clemson has a 4-0 record as a home team as they approach Week 10. They currently rank 2nd in the ACC Conference for home team wins. Continue monitoring their performance to see if they have a shot at a postseason bowl game or playoff berth.
Points Scored - For the 2024 season, Louisville ranks 4th (293) in the ACC Conference, with Clemson currently ranking 3rd (294) for points scored in the ACC Conference.
Points Against - Louisville stands 8th (197) in the ACC Conference for points scored by opponents in the 2024 college football season. Clemson sits at 14th (161) in the ACC Conference for points against them heading into Week 10 of the 2024 season.
Team Records - Louisville has a 5-3 overall record for the 2024 regular season, with Clemson currently 6-1 for the 2024 college football regular season.

Paddy O'Parlay

The "Sports Network" talking heads have nothing on my Irish arse!

Get ready for a wild showdown between Louisville and Clemson on November 2nd!

The Week 10 game will be held at Memorial Stadium in Clemson, SC.

Louisville has a Power Ranking of 94.67 while Clemson has 97.67.

Louisville stands at 5-3 while Clemson boasts a 6-1 record. Place a bet on this college football game at BetMGM or BetRivers. See this matchup's prop bets below. Compare each sportsbook's point spread, total, and moneyline.

Best Cardinals at Tigers Odds

**Best Point Spread Betting Odds**
Underdog Louisville	Favorite Clemson
+10.5 -115 BetMGM Bet	-10.5 -105 BetMGM Bet

Clemson has a -10.5 -105 point spread at BetMGM OH. They are the point spread favorite in this matchup. Louisville has a +10.5 -115 point spread at BetMGM OH. Louisville is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

**Best Total Betting Odds**
Over	Under
62.5 o -105 BetMGM Bet	62.5 u -115 BetMGM Bet

BetMGM has the best over line of 62.5 points. Risk $105 to win $100. BetMGM has the best under line of 62.5 points. Risk $115 to win $100. Our tutorial explains more about total bets.

**Best Moneyline Betting Odds**
Underdog Louisville	Favorite Clemson
+310 BetMGM Bet	-400 BetMGM Bet

Clemson is the -400 moneyline favorite. Risk $400 to win $100 on Clemson at BetMGM. Louisville is the +310 underdog at BetMGM. Risk $100 to win $310 on Louisville. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Louisville vs Clemson College Football game on Saturday, November 2nd, 2024?

Clemson is a -10.5 -105 point spread favorite at BetMGM, while Louisville is a +10.5 -115 point spread underdog at BetMGM.

What is the over-under total line for the Louisville vs Clemson College Football game on Saturday, November 2nd, 2024?

The best over line is 62.5 -105 points at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 62.5 -115 points at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the moneyline for the Louisville vs Clemson College Football game on Saturday, November 2nd, 2024?

Clemson is a -400 moneyline favorite at BetMGM and Louisville is a +310 moneyline underdog at BetMGM.

College Football Odds Example

College Football Odds and Outcomes Explained
Game	BetMGM Bet
Louisville Clemson 11/02/24 7:30pm EDT	+10.5 -115 -10.5 -105

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Underdog Louisville - Louisville bettors risk $100 to win $86.96 at -115 odds.

A +10.5 Louisville underdog bet wins if they lose by 10 or fewer, tie, or win outright. Your bet loses if they lose by 11 or more.

Favorite Clemson - Clemson bettors risk $100 to win $95.24 at -105 odds.

A -10.5 Clemson favorite bet wins if they win by 11 or more. Your bet loses if they win by 10 or fewer, tie, or lose outright.

Louisville at Clemson Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
+ Displays more odds
	BetMGM Bet
Louisville Clemson First Team To Score 11/02/24 7:30pm EDT	+135 -175 Bet
Louisville Clemson No Touchdown To Score 1st Touchdown 11/02/24 7:30pm EDT	+150 -225 +10000 Bet
Louisville Clemson Game to Overtime 11/02/24 7:30pm EDT	Yes +1250 No -10000 Bet
Louisville Clemson Both Teams Score 10+ 11/02/24 7:30pm EDT	Yes -2500 No +900 Bet
	BetMGM
Louisville Clemson Both Teams Score 20+ 11/02/24 7:30pm EDT	Yes -250 No +180 Bet
Louisville Clemson Both Teams Score 30+ 11/02/24 7:30pm EDT	Yes +220 No -300 Bet

Recent Meetings Since 2020

Recent Meetings Since 2020
Week	Game	Result	Margin
2024 Week 10	Louisville vs Clemson Saturday, November 2nd, 2024	LOU 33, CLEM 21 Memorial Stadium (Clemson, SC)	Louisville by 12
2022 Week 11	Louisville vs Clemson Saturday, November 12th, 2022	CLEM 31, LOU 16 Memorial Stadium (Clemson, SC)	Clemson by 15
2021 Week 10	Clemson vs Louisville Saturday, November 6th, 2021	CLEM 30, LOU 24 Cardinal Stadium	Clemson by 6

Team Standings

2024-2025 College Football Regular Season Standings - Louisville, Clemson
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
#12 Clemson	7-1	0.875	10	4	486	328	5-2	4-1	L1
Louisville	5-3	0.625	8	4	439	279	4-2	4-2	W2

Louisville & Clemson Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Louisville Championship Odds

No NCAA College Football Championship TM Louisville YR: futures available

Clemson Championship Odds

No NCAA College Football Championship TM Clemson YR: futures available

Louisville & Clemson Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2024-25 Louisville Games & Results
Week	Matchup	Date & Result
Week 1	Austin Peay vs Louisville	LOU 62, APSU 0 Saturday, August 31st, 2024
Week 2	Jacksonville State vs Louisville	LOU 49, JVST 14 Saturday, September 7th, 2024
Week 4	Georgia Tech vs Louisville	LOU 31, GT 19 Saturday, September 21st, 2024
Week 5	Louisville vs Notre Dame	ND 31, LOU 24 Saturday, September 28th, 2024
Week 6	SMU vs Louisville	SMU 34, LOU 27 Saturday, October 5th, 2024
Week 7	Louisville vs Virginia	LOU 24, UVA 20 Saturday, October 12th, 2024
Week 8	Miami (FL) vs Louisville	MIA 52, LOU 45 Saturday, October 19th, 2024
Week 9	Louisville vs Boston College	LOU 31, BC 27 Friday, October 25th, 2024
Week 10	Louisville vs Clemson	LOU 33, CLEM 21 Saturday, November 2nd, 2024
Week 12	Louisville vs Stanford	STAN 38, LOU 35 Saturday, November 16th, 2024
Week 13	Pittsburgh vs Louisville	LOU 37, PITT 9 Saturday, November 23rd, 2024
Week 14	Louisville vs Kentucky	LOU 41, UK 14 Saturday, November 30th, 2024
Bowls	Louisville vs Washington Tony The Tiger Sun Bowl	Tuesday, December 31st, 2024 2:00 pm EST

2024-25 Clemson Games & Results
Week	Matchup	Date & Result
Week 1	Clemson vs Georgia	UGA 34, CLEM 3 Saturday, August 31st, 2024
Week 2	Appalachian State vs Clemson	CLEM 66, APP 20 Saturday, September 7th, 2024
Week 4	NC State vs Clemson	CLEM 59, NCSU 35 Saturday, September 21st, 2024
Week 5	Stanford vs Clemson	CLEM 40, STAN 14 Saturday, September 28th, 2024
Week 6	Clemson vs Florida State	CLEM 29, FSU 13 Saturday, October 5th, 2024
Week 7	Clemson vs Wake Forest	CLEM 49, WAKE 14 Saturday, October 12th, 2024
Week 8	Virginia vs Clemson	CLEM 48, UVA 31 Saturday, October 19th, 2024
Week 10	Louisville vs Clemson	LOU 33, CLEM 21 Saturday, November 2nd, 2024
Week 11	Clemson vs Virginia Tech	CLEM 24, VT 14 Saturday, November 9th, 2024
Week 12	Clemson vs Pittsburgh	CLEM 24, PITT 20 Saturday, November 16th, 2024
Week 13	The Citadel vs Clemson	CLEM 51, CIT 14 Saturday, November 23rd, 2024
Week 14	South Carolina vs Clemson	SC 17, CLEM 14 Saturday, November 30th, 2024
Week 15	Clemson vs SMU	CLEM 34, SMU 31 Saturday, December 7th, 2024
Bowls	Clemson vs Texas CFP First Round Presented By Allstate	TEX 38, CLEM 24 Saturday, December 21st, 2024

How to Bet on the Game

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How to Bet on the Louisville vs Clemson College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, November 2nd, 2024 at 7:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Louisville vs Clemson Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Louisville vs Clemson Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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