The Cardinals will play the Blue Devils on Saturday, March 15th, 2025. Your timezone's tip off time is 8:30 pm EDT. Check local listings or your nearest streaming app for coverage.
Review our College Basketball Betting guide to learn how to bet this game.
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Table of Contents
- Matchup Stats
- Moneyline Mage
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
The 2024-25 college basketball postseason has arrived. With tournament action on the docket, Louisville and Duke are set to tip-off on Saturday, March 15th, 2025. Here's your chance to partake in March Madness! The end of the regular season has left us with solid trends for each team. Use the following performance insights and stats to handicap what promises to be an exciting matchup.
- SportsBetting3.com Power Rankings - Louisville wound up with a 99.33 SportsBetting3.com conference power ranking for the 2024-25 college basketball regular season, while Duke finished with a 99.67 power ranking.
- Away Records - Tournament games are typically played at neutral venues, which means both teams are away from their home courts. Louisville comes to this matchup with a 9-2 record as an away team, ranking them 2nd in the ACC Conference for away team wins. Their opponent, Duke, finished the regular season with a 10-1 record as an away team, ranking them 1st in the ACC Conference for away team wins.
- Conference Win Percentage - Louisville finished 2nd (0.900) in the ACC Conference, with Duke ending up 1st (0.950) for their conference win percentage in the 2024 ACC Conference.
- Overall Win Percentage - Louisville had a 0.818 regular season overall win percentage, with Duke notching a 0.909 overall win percentage at the end of the 2024-25 regular season.
- Team Records - Louisville tallied a 27-6 regular season overall record. Meanwhile, Duke put together a 30-3 standing for 2024-25 college basketball regular season.
Moneyline Mage
Spelling out the winners with humor since the middle ages.
Hocus pocus, Louisville wizards face off against Duke devils in March Madness clash.
Louisville 27-6, Duke 30-3. Cardinals 18-2 in ACC, Blue Devils 19-1. Single-elimination game.
The tables below have the best point spread lines, total lines, and moneylines for this matchup. Bet on March Madness games at BetRivers and BetMGM. Review this matchup's prop bets below.
Best Cardinals at Blue Devils Odds
| Underdog Louisville | Favorite Duke |
|---|---|
| Over | Under |
|---|---|
| Underdog Louisville | Favorite Duke |
|---|---|
Matchup Odds FAQs
Duke is a -6.5 -110 point spread favorite at BetMGM, while Louisville is a +6.5 -110 point spread underdog at BetMGM.
The best over line is 147.5 -115 points at BetMGM, which means you risk $115 to win $100 betting the over. The best under line is 147.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.
Duke is a -250 moneyline favorite at BetMGM and Louisville is a +200 moneyline underdog at BetMGM.
College Basketball Odds Example
|
Game |
 BetMGMBet |
|---|---|
Louisville
Duke
3/15/25 8:30pm EDT | +6.5 -110-6.5 -110 |
Underdog Louisville - Louisville bettors risk $100 to win $90.91 at -110 odds.
A +6.5 Louisville underdog bet wins if they lose by 6 or fewer, tie, or win outright. Your bet loses if they lose by 7 or more.
Favorite Duke - Duke bettors risk $100 to win $90.91 at -110 odds.
A -6.5 Duke favorite bet wins if they win by 7 or more. Your bet loses if they win by 6 or fewer, tie, or lose outright.
Louisville at Duke Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
| BetMGM Bet |
|
|---|---|
Louisville
Duke
First to 5 Points
3/15/25 8:30pm EDT | +105-145Bet |
Louisville
Duke
First to 10 Points
3/15/25 8:30pm EDT | +115-160Bet |
Louisville
Duke
First to 15 Points
3/15/25 8:30pm EDT | +125-175Bet |
Louisville
Duke
Game to Overtime
3/15/25 8:30pm EDT | Yes +800No -3000Bet |
Team Standings
| Team | W-L | Win% | Home | Away | Conf | CGB | Conf% | Strk |
|---|---|---|---|---|---|---|---|---|
| Duke | 35-3 | 0.921 | 17-0 | 10-1 | 19-1 | - | 0.950 | W15 |
| Louisville | 27-8 | 0.771 | 14-3 | 9-2 | 18-2 | +1 | 0.900 | L2 |
Louisville & Duke Futures Odds
Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.
Louisville Championship OddsNo NCAA Men's Basketball Tournament TM Louisville YR: futures available
Duke Championship Odds|
Team | BetMGM |
|---|---|
| Duke | -110 Bet |
Louisville & Duke Team Pages
Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Louisville vs Duke College Basketball Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, March 15th, 2025 at 8:30 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Basketball page, look for the Louisville vs Duke Game.
Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Louisville vs Duke Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other March 15, 2025 NCAABB Games
- Utah State vs Colorado State - 3/15/25 12:00am EDT
- Maine vs Bryant - 3/15/25 11:00am EDT
- Princeton vs Yale - 3/15/25 11:00am EDT
- Tennessee vs Auburn - 3/15/25 1:00pm EDT
- SC State vs Norfolk State - 3/15/25 1:05pm EDT
- Wisconsin vs Michigan State - 3/15/25 1:07pm EDT
- Loyola Chicago vs VCU - 3/15/25 1:10pm EDT
- Dartmouth vs Cornell - 3/15/25 2:00pm EDT
- Tulane vs Memphis - 3/15/25 3:00pm EDT
- Saint Joseph's vs George Mason - 3/15/25 3:30pm EDT
- Alabama vs Florida - 3/15/25 3:30pm EDT
- Michigan vs Maryland - 3/15/25 3:30pm EDT
- UAB vs North Texas - 3/15/25 5:30pm EDT
- Arizona vs Houston - 3/15/25 6:00pm EDT
- Boise State vs Colorado State - 3/15/25 6:00pm EDT
- Creighton vs St. John's - 3/15/25 6:30pm EDT
- Mount St. Mary's vs Iona - 3/15/25 7:30pm EDT
- Miami (OH) vs Akron - 3/15/25 7:40pm EDT
- Jacksonville State vs Liberty - 3/15/25 8:30pm EDT
- Alabama State vs Jackson State - 3/15/25 9:30pm EDT
- UC Irvine vs UC San Diego - 3/15/25 9:40pm EDT
- Grand Canyon vs Utah Valley - 3/15/25 11:40pm EDT