Creighton vs Louisville Basketball Odds

The Bluejays will play the Cardinals on Thursday, March 20th, 2025. Your timezone's tip off time is 11:15 am CDT. Check local listings or your nearest streaming app for coverage.

Review our College Basketball Betting guide to learn how to bet this game.


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Table of Contents

Key Matchup Stats

The 2024-25 college basketball postseason has arrived. With tournament action on the docket, Creighton and Louisville are set to tip-off on Thursday, March 20th, 2025. Here's your chance to partake in March Madness! The end of the regular season has left us with solid trends for each team. Use the following performance insights and stats to handicap what promises to be an exciting matchup.

  • SportsBetting3.com Power Rankings - Creighton wound up with a 99.00 SportsBetting3.com conference power ranking for the 2024-25 college basketball regular season, while Louisville finished with a 98.33 power ranking.
  • Away Records - Tournament games are typically played at neutral venues, which means both teams are away from their home courts. Creighton comes to this matchup with a 6-6 record as an away team, ranking them 3rd in the Big East Conference for away team wins. Their opponent, Louisville, finished the regular season with a 9-2 record as an away team, ranking them 2nd in the ACC Conference for away team wins.
  • Conference Win Percentage - Creighton finished 2nd (0.750) in the Big East Conference, with Louisville ending up 2nd (0.900) for their conference win percentage in the 2024 ACC Conference.
  • Overall Win Percentage - Creighton had a 0.706 regular season overall win percentage, with Louisville notching a 0.794 overall win percentage at the end of the 2024-25 regular season.
  • Team Records - Creighton tallied a 24-10 regular season overall record. Meanwhile, Louisville put together a 27-7 standing for 2024-25 college basketball regular season.

Moneyline Mage

Spelling out the winners with humor since the middle ages.

Moneyline Mage
Moneyline Mage

Prepare for a magical battle between Creighton and Louisville in March Madness!

Creighton at 24-10 versus Louisville at 27-7 for a thrilling showdown.

The tables below have the best point spread lines, total lines, and moneylines for this matchup. Bet on March Madness games at BetRivers and BetMGM. Review this matchup's prop bets below.

Best Bluejays at Cardinals Odds


Best Point Spread Betting Odds
Underdog

Creighton
Favorite

Louisville
Louisville has a -3 -109 point spread at BetRivers PA. They are the point spread favorite in this matchup. Creighton has a +3.5 -115 point spread at BetMGM PA. Creighton is the point spread underdog. Review how to bet on a point spread with our text and video tutorials.

Best Total Betting Odds
OverUnder
BetRivers has the best over line of 145.5 points. Risk $109 to win $100. BetMGM has the best under line of 145.5 points. Risk $110 to win $100. Our tutorial explains more about total bets.

Best Moneyline Betting Odds
Underdog

Creighton
Favorite

Louisville
Louisville is the -150 moneyline favorite. Risk $150 to win $100 on Louisville at BetMGM. Creighton is the +130 underdog at BetRivers. Risk $100 to win $130 on Creighton. Learn more about how to bet on money lines.

Matchup Odds FAQs

What is the point spread for the Creighton vs Louisville College Basketball game on Thursday, March 20th, 2025?

Louisville is a -3 -109 point spread favorite at BetRivers, while Creighton is a +3.5 -115 point spread underdog at BetMGM.

What is the over-under total line for the Creighton vs Louisville College Basketball game on Thursday, March 20th, 2025?

The best over line is 145.5 -109 points at BetRivers, which means you risk $109 to win $100 betting the over. The best under line is 145.5 -110 points at BetMGM, and that means you risk $110 to win $100 betting the under.

What is the moneyline for the Creighton vs Louisville College Basketball game on Thursday, March 20th, 2025?

Louisville is a -150 moneyline favorite at BetMGM and Creighton is a +130 moneyline underdog at BetRivers.

College Basketball Odds Example

College Basketball Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Creighton
Louisville
3/20/25 11:15am CDT
+3.5 -115-3.5 -105
Bet $100 at BetMGM Pennsylvania
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Underdog Creighton - Creighton bettors risk $100 to win $86.96 at -115 odds.

A +3.5 Creighton underdog bet wins if they lose by 3 or fewer, tie, or win outright. Your bet loses if they lose by 4 or more.

Favorite Louisville - Louisville bettors risk $100 to win $95.24 at -105 odds.

A -3.5 Louisville favorite bet wins if they win by 4 or more. Your bet loses if they win by 3 or fewer, tie, or lose outright.

Creighton at Louisville Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Basketball Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Creighton
Louisville
First to 5 Points
3/20/25 11:15am CDT
-105-135Bet
Creighton
Louisville
First to 10 Points
3/20/25 11:15am CDT
+100-140Bet
Creighton
Louisville
First to 15 Points
3/20/25 11:15am CDT
+105-145Bet
Creighton
Louisville
Game to Overtime
3/20/25 11:15am CDT
Yes +800No -3000Bet

Team Standings

2024-2025 College Basketball Regular Season Standings - Creighton, Louisville
Team W-L Win% Home Away Conf CGB Conf% Strk
ACC
Louisville27-80.77114-39-218-2+10.900L2
Big East
Creighton25-110.69415-26-615-5+30.750L1

Creighton & Louisville Futures Odds

Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.

Creighton Championship Odds

No NCAA Men's Basketball Tournament TM Creighton YR: futures available

Louisville Championship Odds

No NCAA Men's Basketball Tournament TM Louisville YR: futures available

Creighton & Louisville Team Pages

Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the Creighton vs Louisville College Basketball Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Thursday, March 20th, 2025 at 11:15 am CDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's College Basketball page, look for the Creighton vs Louisville Game.

    Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Creighton vs Louisville Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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