The Tigers will play the Cardinals on Friday, March 14th, 2025. Your timezone's tip off time is 8:30 pm CDT. Check local listings or your nearest streaming app for coverage.
Review our College Basketball Betting guide to learn how to bet this game.
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Table of Contents
- Matchup Stats
- Moneyline Mage
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Standings
- Futures Odds
- Team Pages
- Other Games Today
Key Matchup Stats
The 2024-25 college basketball postseason has arrived. With tournament action on the docket, Clemson and Louisville are set to tip-off on Friday, March 14th, 2025. Here's your chance to partake in March Madness! The end of the regular season has left us with solid trends for each team. Use the following performance insights and stats to handicap what promises to be an exciting matchup.
- SportsBetting3.com Power Rankings - Clemson wound up with a 99.00 SportsBetting3.com conference power ranking for the 2024-25 college basketball regular season, while Louisville finished with a 99.00 power ranking.
- Away Records - Tournament games are typically played at neutral venues, which means both teams are away from their home courts. Clemson comes to this matchup with a 9-3 record as an away team, ranking them 2nd in the ACC Conference for away team wins. Their opponent, Louisville, finished the regular season with a 9-2 record as an away team, ranking them 2nd in the ACC Conference for away team wins.
- Conference Win Percentage - Clemson finished 2nd (0.900) in the ACC Conference, with Louisville ending up 2nd (0.900) for their conference win percentage in the 2024 ACC Conference.
- Overall Win Percentage - Clemson had a 0.844 regular season overall win percentage, with Louisville notching a 0.813 overall win percentage at the end of the 2024-25 regular season.
- Team Records - Clemson tallied a 27-5 regular season overall record. Meanwhile, Louisville put together a 26-6 standing for 2024-25 college basketball regular season.
Moneyline Mage
Spelling out the winners with humor since the middle ages.

Hocus pocus, Friday night madness, Clemson and Louisville clash on the court.
Clemson 27-5 overall, Louisville 26-6. Both 18-2 in ACC Conference standings.
The tables below have the best point spread lines, total lines, and moneylines for this matchup. Bet on March Madness games at BetRivers and BetMGM. Review this matchup's prop bets below.
Best Tigers at Cardinals Odds
Underdog Louisville | Favorite Clemson |
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Over | Under |
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Underdog Louisville | Favorite Clemson |
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Matchup Odds FAQs
Clemson is a -1.5 -108 point spread favorite at BetRivers, while Louisville is a +1.5 -102 point spread underdog at BetMGM.
The best over line is 141.5 -107 points at BetRivers, which means you risk $107 to win $100 betting the over. The best under line is 141.5 -105 points at BetMGM, and that means you risk $105 to win $100 betting the under.
Clemson is a -127 moneyline favorite at BetRivers and Louisville is a +110 moneyline underdog at BetMGM.
College Basketball Odds Example
Game |
![]() Bet |
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Clemson
Louisville
3/14/25 8:30pm CDT | -1.5 -118+1.5 -102 |
Underdog Louisville - Louisville bettors risk $100 to win $98.04 at -102 odds.
A +1.5 Louisville underdog bet wins if they lose by 1, tie, or win outright. Your bet loses if they lose by 2 or more.
Favorite Clemson - Clemson bettors risk $100 to win $84.75 at -118 odds.
A -1.5 Clemson favorite bet wins if they win by 2 or more. Your bet loses if they win by 1, tie, or lose outright.
Clemson at Louisville Prop Bets
Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.
![]() Bet |
|
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Clemson
Louisville
First to 5 Points
3/14/25 8:30pm CDT | -125-110Bet |
Clemson
Louisville
First to 10 Points
3/14/25 8:30pm CDT | -125-110Bet |
Clemson
Louisville
First to 15 Points
3/14/25 8:30pm CDT | -125-110Bet |
Clemson
Louisville
Game to Overtime
3/14/25 8:30pm CDT | Yes +700No -2000Bet |
Team Standings
Team | W-L | Win% | Home | Away | Conf | CGB | Conf% | Strk |
---|---|---|---|---|---|---|---|---|
#22 Clemson | 27-7 | 0.794 | 15-2 | 9-3 | 18-2 | +1 | 0.900 | L2 |
#21 Louisville | 27-8 | 0.771 | 14-3 | 9-2 | 18-2 | +1 | 0.900 | L2 |
Clemson & Louisville Futures Odds
Latest College Basketball Championship odds, if available, for each team. Review March Madness odds for other teams and learn how to bet on the college basketball tournament. Also be sure to read Ron Halfback's Final Four write-up.
Clemson Championship OddsNo NCAA Men's Basketball Tournament TM Clemson YR: futures available
Louisville Championship OddsNo NCAA Men's Basketball Tournament TM Louisville YR: futures available
Clemson & Louisville Team Pages
Review each team's futures odds, betting bonuses, current standings and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Clemson vs Louisville College Basketball Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Friday, March 14th, 2025 at 8:30 pm CDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's College Basketball page, look for the Clemson vs Louisville Game.
Navigate to the sportsbook's College Basketball page. Next, look for live or upcoming matchups. Select the Clemson vs Louisville Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other March 14, 2025 NCAABB Games
- St. Bonaventure vs VCU
- Oregon vs Michigan State
- Kennesaw State vs Liberty
- Wichita State vs Memphis
- Ole Miss vs Auburn
- Saint Louis vs Loyola Chicago
- Grambling State vs Alabama State
- Wisconsin vs UCLA
- Florida Atlantic vs Tulane
- Middle Tennessee vs Jacksonville State
- Texas vs Tennessee
- Toledo vs Akron
- George Washington vs George Mason
- Morgan State vs Norfolk State
- Iona vs Quinnipiac
- Marquette vs St. John's
- Illinois vs Maryland
- Missouri vs Florida
- Tulsa vs North Texas
- North Carolina vs Duke
- BYU vs Houston
- Saint Joseph's vs Dayton
- Kent State vs Miami (OH)
- NCCU vs SC State
- Mount St. Mary's vs Merrimack
- Bethune-Cookman vs Jackson State
- Seattle vs Utah Valley
- UC Santa Barbara vs UC San Diego
- Purdue vs Michigan
- East Carolina vs UAB
- UConn vs Creighton
- Arizona vs Texas Tech
- Kentucky vs Alabama
- Boise State vs New Mexico
- Cal Poly vs UC Irvine
- California Baptist vs Grand Canyon