San Diego Padres vs Chicago Cubs Odds

The Padres will play the Cubs on Friday, April 4th, 2025. Your timezone's first pitch time is 2:20 pm EDT. Check local listings or your nearest streaming app for coverage.

Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.


Bonus
BetMGM Sportsbook#1 BetMGM
REVIEW
New Customers - Up to $1500 Paid Back in Bonus Bets
Bonus Bets Expire in 7 Days
One new customer offer/Add'l Terms

Bet Now
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966

Table of Contents

Key Matchup Stats

  • SportsBetting3.com Power Rankings - The San Diego Padres have a 99.33 power ranking. The power ranking for the Chicago Cubs is 96.00.
  • Visiting San Diego Padres - The San Diego Padres have a 0-0 record as a visiting team, ranking them 6th Overall for visiting team wins.
  • Home Chicago Cubs - The Chicago Cubs have a 0-2 record as a home team. They rank 8th for home team wins in the Overall standings.
  • Runs Scored - The San Diego Padres currently stand 6th (36) Overall, with the Chicago Cubs ranking 1st (60) for runs scored.
  • Runs Allowed - The San Diego Padres are 16th (11) Overall for runs allowed. The Chicago Cubs stand 2nd (46) for runs allowed.
  • Team Streaks - The San Diego Padres have won their last 7 games. Meanwhile, the Chicago Cubs have won their last 3 games.
  • Team Records - The San Diego Padres have a 7-0 Overall record (0.5 GB National West Division), with the Chicago Cubs possessing a 5-4 Overall standing (0.5 GB National Central Division).

Captain Shady Lines

A broken compass is right at least twice a day.

Captain Shady Lines
Captain Shady Lines

Avast ye mateys! The Padres be setting sail to face the Cubs...

With a perfect record, they be lookin' to plunder another victory on enemy soil...

If ye be brave enough, head to SportsBetting3.com, bet on this game, and review the odds below!

Best Padres at Cubs Odds


Best Moneyline Betting Odds
Underdog

San Diego Padres
Favorite

Chicago Cubs
The Chicago Cubs are the -165 moneyline favorite. Risk $165 to win $100 on the Chicago Cubs at BetMGM. The San Diego Padres are the +140 underdog at BetMGM. Risk $100 to win $140 on the San Diego Padres. Learn more about how to bet on money lines.

Best Total Betting Odds
OverUnder
BetMGM has the best over line of 7 runs. Risk $105 to win $100. BetMGM has the best under line of 7 runs. Risk $115 to win $100. Our tutorial explains more about total bets.

Best Run Line Betting Odds
Underdog

San Diego Padres
Favorite

Chicago Cubs
The Chicago Cubs have a -1.5 +140 run line at BetMGM OH. They are the run line favorite in this matchup. The San Diego Padres have a +1.5 -165 run line at BetMGM OH. The San Diego Padres are the run line underdogs. Review how to bet on a point spread with our text and video tutorials.

Matchup Odds FAQs

What is the moneyline for the San Diego Padres vs Chicago Cubs MLB game on Friday, April 4th, 2025?

The Chicago Cubs are the -165 moneyline favorite at BetMGM and the San Diego Padres are the +140 moneyline underdog at BetMGM.

What is the over-under total line for the San Diego Padres vs Chicago Cubs MLB game on Friday, April 4th, 2025?

The best over line is 7 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.

What is the run line for the San Diego Padres vs Chicago Cubs MLB game on Friday, April 4th, 2025?

The Chicago Cubs are -1.5 +140 run line favorites at BetMGM, while the San Diego Padres are +1.5 -165 run line underdogs at BetMGM.

MLB Odds Example

MLB Odds and Outcomes Explained

Game
BetMGM Sports Betting BetMGM
Bet
Padres
Cubs
2:20pm EDT
+140-165
Bet $100 at BetMGM Ohio
21+ Playable in Ohio only
Gambling Problem? Call 1-800-589-9966
Possible Moneyline Outcomes
  • San Diego Padres bettors risk $100 to win $140 at +140 odds. The implied probability for San Diego Padres is 41.67%.
  • Chicago Cubs bettors risk $100 to win $60.61 at -165 odds. The implied probability for Chicago Cubs is 62.26%.

San Diego Padres at Chicago Cubs Prop Bets

MLB Prop Bets
+ Displays more odds
BetMGM Sports Betting BetMGM
Bet
Padres
Cubs
First Team to Score
2:20pm EDT
-115-110Bet
Padres
Cubs
Tie
1st Inning Winner
2:20pm EDT
+400+300-170Bet
Padres
Cubs
Tie
First 3 Innings Winner
2:20pm EDT
+200+120+230Bet
Padres
Cubs
To Extra Innings
2:20pm EDT
Yes +700No -1100Bet
BetMGM Sports Betting BetMGM
Padres
Cubs
1st Team to Score Will Win
2:20pm EDT
Yes -250No +190Bet
Cubs
Total Runs
SDG at CUB
2:20pm EDT
3.5 o -1253.5 u -105Bet
Padres
Total Runs
SDG at CUB
2:20pm EDT
2.5 o -1502.5 u +115Bet
Shota Imanaga
Strikeouts Thrown
SDG at CUB
2:20pm EDT
4.5 o -1654.5 u +125Bet

San Diego Padres & Chicago Cubs Futures Odds

Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.

San Diego Padres World Series Odds
2025 San Diego Padres World Series Odds

Team
BetMGM Sports Betting BetMGM
Padres
+2200
Bet
Chicago Cubs World Series Odds
2025 Chicago Cubs World Series Odds

Team
BetMGM Sports Betting BetMGM
Cubs
+2500
Bet

San Diego Padres & Chicago Cubs Team Pages

Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Standings

2025 MLB Regular Season Standings - San Diego Padres, Chicago Cubs
Team W L Pct GB Home Away RS RA Diff Strk L10
San Diego Padres701.000+0.57-00-03611+25W77-0
Chicago Cubs540.556+3.50-25-26046+14W35-4

How to Bet on the Game

Time needed: 4 minutes.

How to Bet on the San Diego Padres vs Chicago Cubs MLB Game

  1. Open a new sports betting account before game time.

    Review our list of sports betting sites. Open a new account before the game starts on Friday, April 4th, 2025 at 2:20 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.

  2. Visit the sportsbook’s cashier, banking, or deposit page.

    Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.

  3. Tap to the sportsbook's MLB page, look for the San Diego Padres vs Chicago Cubs Game.

    Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Diego Padres vs Chicago Cubs Game.

  4. Choose your bet and place a wager.

    Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

Other April 4, 2025 MLB Games

Odds Preview 12001