The Padres will play the Astros on Friday, April 18th, 2025. Your timezone's first pitch time is 8:10 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
| Bonus | |
|---|---|
 #1 BetMGMREVIEW | New Customers - Up to $1500 Paid Back in Bonus Bets Bonus Bets Expire in 7 Days One new customer offer/Add'l Terms Bet Now 21+ Playable in Ohio only Gambling Problem? Call 1-800-589-9966 |
Table of Contents
- Matchup Stats
- Captain Shady Lines
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Key Matchup Stats
- SportsBetting3.com Power Rankings - The San Diego Padres have a 99.33 power ranking. The power ranking for the Houston Astros is 92.00.
- Visiting San Diego Padres - The San Diego Padres have a 3-3 record as a visiting team, ranking them 6th Overall for visiting team wins.
- Home Houston Astros - The Houston Astros have a 4-5 record as a home team. They rank 7th for home team wins in the Overall standings.
- Runs Scored - The San Diego Padres currently stand 7th (88) Overall, with the Houston Astros ranking 19th (66) for runs scored.
- Runs Allowed - The San Diego Padres are 24th (51) Overall for runs allowed. The Houston Astros stand 17th (70) for runs allowed.
- Team Streaks - The San Diego Padres won their last game. Meanwhile, the Houston Astros lost their last game.
- Team Records - The San Diego Padres have a 15-4 Overall record (0.0 GB National West Division), with the Houston Astros possessing a 8-10 Overall standing (2.5 GB American West Division).
Captain Shady Lines
A broken compass is right at least twice a day.
Avast ye, Padres be sailing into enemy waters to plunder victory... (But beware Astros be ready to defend their turf with all their might!)... The Padres be a fearsome force with a record that strikes fear.
SportsBetting3.com be the place to be, savvy? Ye best be ready to bet on this game... Review the odds below and place your wagers wisely, lest ye walk the plank.
The Astros may be struggling, but a wounded beast be the most dangerous... (Padres best be on high alert if they want to leave with plunder!)... Friday be a battle for supremacy, may the best team emerge victorious.
Best Padres at Astros Odds
| Underdog San Diego Padres | Favorite Houston Astros |
|---|---|
| Over | Under |
|---|---|
| Underdog San Diego Padres | Favorite Houston Astros |
|---|---|
Matchup Odds FAQs
The Houston Astros are the -155 moneyline favorite at BetMGM and the San Diego Padres are the +130 moneyline underdog at BetMGM.
The best over line is 9 +100 runs at BetMGM, which means you risk $100 to win $100 betting the over. The best under line is 9 -120 runs at BetMGM, and that means you risk $120 to win $100 betting the under.
The Houston Astros are -1.5 +140 run line favorites at BetMGM, while the San Diego Padres are +1.5 -170 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Padres
Astros
8:10pm EDT | +130-155 |
- San Diego Padres bettors risk $100 to win $130 at +130 odds. The implied probability for San Diego Padres is 43.48%.
- Houston Astros bettors risk $100 to win $64.52 at -155 odds. The implied probability for Houston Astros is 60.78%.
San Diego Padres at Houston Astros Prop Bets
| BetMGM Bet |
|
|---|---|
Padres
Astros
First Team to Score
8:10pm EDT | -135+105Bet |
Padres
Astros
Tie
1st Inning Winner
8:10pm EDT | +310+250-120Bet |
Padres
Astros
Tie
First 3 Innings Winner
8:10pm EDT | +165+110+310Bet |
Padres
Astros
To Extra Innings
8:10pm EDT | Yes +800No -1400Bet |
| BetMGM | |
Padres
Astros
1st Team to Score Will Win
8:10pm EDT | Yes -250No +190Bet |
Astros
Total Runs
SDG at HOU 8:10pm EDT | 4.5 o -1104.5 u -115Bet |
Padres
Total Runs
SDG at HOU 8:10pm EDT | 3.5 o -1453.5 u +110Bet |
Kyle Hart
Strikeouts Thrown
SDG at HOU 8:10pm EDT | 3.5 o +1003.5 u -135Bet |
| BetMGM | |
Ryan Gusto
Strikeouts Thrown
SDG at HOU 8:10pm EDT | 4.5 o +1354.5 u -185Bet |
San Diego Padres & Houston Astros Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
San Diego Padres World Series Odds|
Team | BetMGM |
|---|---|
| Padres | +2200 Bet |
|
Team | BetMGM |
|---|---|
| Astros | +2200 Bet |
San Diego Padres & Houston Astros Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| San Diego Padres | 15 | 4 | 0.789 | 0.0 | 12-1 | 3-3 | 88 | 51 | +37 | W1 | 8-2 |
| Houston Astros | 8 | 10 | 0.444 | +6.5 | 4-5 | 4-5 | 66 | 70 | -4 | L1 | 5-5 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the San Diego Padres vs Houston Astros MLB Game
-
Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Friday, April 18th, 2025 at 8:10 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
-
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
-
Tap to the sportsbook's MLB page, look for the San Diego Padres vs Houston Astros Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the San Diego Padres vs Houston Astros Game.
-
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other April 18, 2025 MLB Games
- Arizona Diamondbacks vs Chicago Cubs - 2:20pm EDT
- Kansas City Royals vs Detroit Tigers - 6:40pm EDT
- Cleveland Guardians vs Pittsburgh Pirates - 6:40pm EDT
- Miami Marlins vs Philadelphia Phillies - 6:45pm EDT
- Cincinnati Reds vs Baltimore Orioles - 7:05pm EDT
- New York Yankees vs Tampa Bay Rays - 7:05pm EDT
- Seattle Mariners vs Toronto Blue Jays - 7:07pm EDT
- St. Louis Cardinals vs New York Mets - 7:10pm EDT
- Chicago White Sox vs Boston Red Sox - 7:10pm EDT
- Minnesota Twins vs Atlanta Braves - 7:15pm EDT
- Los Angeles Dodgers vs Texas Rangers - 8:05pm EDT
- Oakland Athletics vs Milwaukee Brewers - 8:10pm EDT
- Washington Nationals vs Colorado Rockies - 8:40pm EDT
- San Francisco Giants vs Los Angeles Angels - 9:38pm EDT