The Guardians will play the Cardinals on Sunday, September 22nd, 2024. Your timezone's first pitch time is 2:15 pm EDT. Check local listings or your nearest streaming app for coverage.
Learn more about MLB Betting with our handy tutorial and guide. We explain money line, total and run line bets. Plus, a great discussion about exotic bets like MLB Baseball parlays and props.
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Table of Contents
- Best Odds
- Interactive Odds Example
- Prop Bets
- Team Futures Odds
- Team Pages
- Team Standings
- Other Games Today
Best Guardians at Cardinals Odds
| Underdog Cleveland Guardians | Favorite St. Louis Cardinals |
|---|---|
| Over | Under |
|---|---|
| Underdog St. Louis Cardinals | Favorite Cleveland Guardians |
|---|---|
Matchup Odds FAQs
The St. Louis Cardinals are the -120 moneyline favorite at BetMGM and the Cleveland Guardians are the +100 moneyline underdog at BetMGM.
The best over line is 7.5 -105 runs at BetMGM, which means you risk $105 to win $100 betting the over. The best under line is 7.5 -115 runs at BetMGM, and that means you risk $115 to win $100 betting the under.
The Cleveland Guardians are -1.5 +170 run line favorites at BetMGM, while the St. Louis Cardinals are +1.5 -210 run line underdogs at BetMGM.
MLB Odds Example
|
Game |
 BetMGMBet |
|---|---|
Guardians
Cardinals
9/22/24 2:15pm EDT | +100-120 |
- Cleveland Guardians bettors risk $100 to win $100 at +100 odds. The implied probability for Cleveland Guardians is 50%.
- St. Louis Cardinals bettors risk $100 to win $83.33 at -120 odds. The implied probability for St. Louis Cardinals is 54.55%.
Cleveland Guardians at St. Louis Cardinals Prop Bets
| BetMGM Bet |
|
|---|---|
Guardians
Cardinals
First Team to Score
9/22/24 2:15pm EDT | -140+110Bet |
Guardians
Cardinals
Tie
1st Inning Winner
9/22/24 2:15pm EDT | +333+320-155Bet |
Guardians
Cardinals
Tie
First 3 Innings Winner
9/22/24 2:15pm EDT | +160+140+250Bet |
Guardians
Cardinals
To Extra Innings
9/22/24 2:15pm EDT | Yes +725No -1200Bet |
| BetMGM | |
Guardians
Cardinals
1st Team to Score Will Win
9/22/24 2:15pm EDT | Yes -250No +190Bet |
Guardians
Total Runs
CLE at STL 9/22/24 2:15pm EDT | 3.5 o -1203.5 u -110Bet |
Cardinals
Total Runs
CLE at STL 9/22/24 2:15pm EDT | 3.5 o -1253.5 u -105Bet |
Andre Pallante
Strikeouts Thrown
CLE at STL 9/22/24 2:15pm EDT | 4.5 o +1204.5 u -160Bet |
| BetMGM | |
Gavin Williams
Strikeouts Thrown
CLE at STL 9/22/24 2:15pm EDT | 5.5 o +1155.5 u -150Bet |
Cleveland Guardians & St. Louis Cardinals Futures Odds
Latest World Series odds, if available, for each team. Review odds for other teams and learn how to bet on the tournament. See past Championship results and learn how to bet World Series teasers, props and parlays.
Cleveland Guardians World Series OddsNo World Series TM Cleveland Guardians YR: futures available
St. Louis Cardinals World Series OddsNo World Series TM St. Louis Cardinals YR: futures available
Cleveland Guardians & St. Louis Cardinals Team Pages
Review each team's season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:
Team Standings
| Team | W | L | Pct | GB | Home | Away | RS | RA | Diff | Strk | L10 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| x - Cleveland Guardians | 92 | 69 | 0.571 | +5.5 | 50-30 | 42-39 | 708 | 621 | +87 | L2 | 5-5 |
| e - St. Louis Cardinals | 83 | 79 | 0.512 | +15.0 | 44-37 | 39-42 | 672 | 719 | -47 | W1 | 6-4 |
How to Bet on the Game
Time needed: 4 minutes.
How to Bet on the Cleveland Guardians vs St. Louis Cardinals MLB Game
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Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Sunday, September 22nd, 2024 at 2:15 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
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Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
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Tap to the sportsbook's MLB page, look for the Cleveland Guardians vs St. Louis Cardinals Game.
Navigate to the sportsbook's MLB page. Next, look for live or upcoming matchups. Select the Cleveland Guardians vs St. Louis Cardinals Game.
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Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.
Other September 22, 2024 MLB Games
- Pittsburgh Pirates vs Cincinnati Reds
- Detroit Tigers vs Baltimore Orioles
- Toronto Blue Jays vs Tampa Bay Rays
- Atlanta Braves vs Miami Marlins
- Los Angeles Angels vs Houston Astros
- San Francisco Giants vs Kansas City Royals
- Arizona Diamondbacks vs Milwaukee Brewers
- Washington Nationals vs Chicago Cubs
- Seattle Mariners vs Texas Rangers
- New York Yankees vs Oakland Athletics
- Colorado Rockies vs Los Angeles Dodgers
- Chicago White Sox vs San Diego Padres
- Minnesota Twins vs Boston Red Sox
- Philadelphia Phillies vs New York Mets