The Cardinals will play the Orange on Saturday, September 3rd, 2022. The matchup takes place at JMA Wireless Dome. Watch this exciting Week 1 matchup at 8:00 pm EDT. Check local listings for coverage on ACCN.

Learn more about College Football betting with our handy tutorial and guide. We explain spread, total and money line bets.

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Best Cardinals at Orange Odds

**Best Point Spread Betting Odds**
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**Best Total Betting Odds**
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**Best Moneyline Betting Odds**
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Louisville at Syracuse Prop Bets

Important Note: Some states expressly forbid individual college athlete prop bets. The following wagers may not be available depending on your particular state laws.

College Football Prop Bets
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	BetMGM Bet
Louisville Syracuse 9/03/22 8:00pm EDT	Pending BetMGM

Recent Meetings Since 2018

Recent Meetings Since 2018
Week	Game	Result	Margin
2022 Week 1	Louisville vs Syracuse Saturday, September 3rd, 2022	SYR 31, LOU 7 JMA Wireless Dome	Syracuse by 24
2021 Week 11	Syracuse vs Louisville Saturday, November 13th, 2021	LOU 41, SYR 3 Cardinal Stadium	Louisville by 38
2020 Week 12	Syracuse vs Louisville Friday, November 20th, 2020	LOU 30, SYR 0 Cardinal Stadium	Louisville by 30
2019 Week 13	Syracuse vs Louisville Saturday, November 23rd, 2019	LOU 56, SYR 34 Cardinal Stadium	Louisville by 22
2018 Week 11	Louisville vs Syracuse Friday, November 9th, 2018	SYR 54, LOU 23 JMA Wireless Dome	Syracuse by 31

Team Standings

2022-2023 College Football Regular Season Standings - Louisville, Syracuse
Team	Conf	Conf%	W	L	PF	PA	Home	Away	Strk
Louisville	4-4	0.500	8	5	350	249	5-1	2-4	W1
Syracuse	4-4	0.500	7	6	360	300	5-2	2-3	L1

Louisville & Syracuse Futures Odds

Latest NCAA Championship odds, if available, for each team. Review odds for other teams and learn the best College Football bets.

Louisville Championship Odds

2024-25 Louisville NCAA College Football Championship Odds
Team	BetMGM
Louisville

Syracuse Championship Odds

No NCAA College Football Championship TM Syracuse YR: futures available

Louisville & Syracuse Team Pages

Review each team's season schedule and results, season win total odds, futures odds, betting bonuses and other valuable information on our exclusive team betting odds pages. Team betting odds and stats update throughout the season:

Team Schedules & Results

2022-23 Louisville Games & Results
Week	Matchup	Date & Result
Week 1	Louisville vs Syracuse	SYR 31, LOU 7 Saturday, September 3rd, 2022
Week 2	Louisville vs UCF	LOU 20, UCF 14 Friday, September 9th, 2022
Week 3	Florida State vs Louisville	FSU 35, LOU 31 Friday, September 16th, 2022
Week 4	South Florida vs Louisville	LOU 41, USF 3 Saturday, September 24th, 2022
Week 5	Louisville vs Boston College	BC 34, LOU 33 Saturday, October 1st, 2022
Week 6	Louisville vs Virginia	LOU 34, UVA 17 Saturday, October 8th, 2022
Week 8	Pittsburgh vs Louisville	LOU 24, PITT 10 Saturday, October 22nd, 2022
Week 9	Wake Forest vs Louisville	LOU 48, WAKE 21 Saturday, October 29th, 2022
Week 10	James Madison vs Louisville	LOU 34, JMU 10 Saturday, November 5th, 2022
Week 11	Louisville vs Clemson	CLEM 31, LOU 16 Saturday, November 12th, 2022
Week 12	NC State vs Louisville	LOU 25, NCST 10 Saturday, November 19th, 2022
Week 13	Louisville vs Kentucky	UK 26, LOU 13 Saturday, November 26th, 2022
Bowls	Cincinnati vs Louisville Wasabi Fenway Bowl	LOU 24, CIN 7 Saturday, December 17th, 2022

2022-23 Syracuse Games & Results
Week	Matchup	Date & Result
Week 1	Louisville vs Syracuse	SYR 31, LOU 7 Saturday, September 3rd, 2022
Week 2	Syracuse vs UConn	SYR 48, CONN 14 Saturday, September 10th, 2022
Week 3	Purdue vs Syracuse	SYR 32, PUR 29 Saturday, September 17th, 2022
Week 4	Virginia vs Syracuse	SYR 22, UVA 20 Friday, September 23rd, 2022
Week 5	Wagner vs Syracuse	SYR 59, WAG 0 Saturday, October 1st, 2022
Week 7	NC State vs Syracuse	SYR 24, NCST 9 Saturday, October 15th, 2022
Week 8	Syracuse vs Clemson	CLEM 27, SYR 21 Saturday, October 22nd, 2022
Week 9	Notre Dame vs Syracuse	ND 41, SYR 24 Saturday, October 29th, 2022
Week 10	Syracuse vs Pittsburgh	PITT 19, SYR 9 Saturday, November 5th, 2022
Week 11	Florida State vs Syracuse	FSU 38, SYR 3 Saturday, November 12th, 2022
Week 12	Syracuse vs Wake Forest	WAKE 45, SYR 35 Saturday, November 19th, 2022
Week 13	Syracuse vs Boston College	SYR 32, BC 23 Saturday, November 26th, 2022
Bowls	Syracuse vs Minnesota Bad Boy Mowers Pinstripe Bowl	MINN 28, SYR 20 Thursday, December 29th, 2022

How to Bet on the Game

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How to Bet on the Louisville vs Syracuse College Football Game

Open a new sports betting account before game time.
Review our list of sports betting sites. Open a new account before the game starts on Saturday, September 3rd, 2022 at 8:00 pm EDT, making sure to enter all your personal details correctly. Don't forget to add your bonus code.
Visit the sportsbook’s cashier, banking, or deposit page.
Navigate to the sportsbook's deposit page. Use your Visa card or MasterCard, or deposit with a bank transfer, or other methods like Paypal.
Tap to the sportsbook's College Football page, look for the Louisville vs Syracuse Game.
Navigate to the sportsbook's College Football page. Next, look for live or upcoming matchups. Select the Louisville vs Syracuse Game.
Choose your bet and place a wager.
Choose your bet and then use the funds you deposited to place a wager. The sportsbook will pay your winnings or deduct a losing wager from your account balance after the game.

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